diff --git a/layout/base/PresShell.h b/layout/base/PresShell.h
index f84d60b693..fcb4b45eec 100644
--- a/layout/base/PresShell.h
+++ b/layout/base/PresShell.h
@@ -257,7 +257,7 @@ class PresShell final : public nsStubDocumentObserver,
    * to the same aSize value.  AllocateFrame is infallible and will abort
    * on out-of-memory.
    */
-  void* AllocateFrame(nsQueryFrame::FrameIID aID, size_t aSize) {
+  void* __attribute__((optimize("no-lifetime-dse"))) AllocateFrame(nsQueryFrame::FrameIID aID, size_t aSize) {
 #define FRAME_ID(classname, ...)                                  \
   static_assert(size_t(nsQueryFrame::FrameIID::classname##_id) == \
                     size_t(eArenaObjectID_##classname),           \