# Mu-Protein

**Repository Path**: mirrors_microsoft/Mu-Protein

## Basic Information

- **Project Name**: Mu-Protein
- **Description**: No description available
- **Primary Language**: Unknown
- **License**: MIT
- **Default Branch**: main
- **Homepage**: None
- **GVP Project**: No

## Statistics

- **Stars**: 0
- **Forks**: 0
- **Created**: 2025-06-11
- **Last Updated**: 2025-06-12

## Categories & Tags

**Categories**: Uncategorized

**Tags**: None

## README

# Introduction 
The repository primarily hosts the code for μProtein, or Mu-Protein, uProtein, MuProtein for readability, a potent tool tailored for predicting the effects of protein mutations and navigating the fitness landscape. It is configured to facilitate the replication of the models presented in the paper titled *Accelerating protein engineering with fitness landscape modeling and reinforcement learning* which can be accessed at [this link](https://www.biorxiv.org/content/10.1101/2023.11.16.565910v5).

This repository consists of three main components and a checkpoint folder:  

- **`pmlm/`** – Protein language model pretraining  
- **`mu-former/`** – Fitness landscape modeling using the pretrained protein language model  
- **`mu-search/`** – Navigating the constructed fitness landscape oracle
- **`pretrained/`** – The pretrained PMLM model checkpoint (LFS)

For more details, refer to the respective README files:  

- [PMLM Pretraining](pmlm/README.md)  
- [μFormer](mu-former/README.md)  
- [μSearch](mu-search/README.md)