diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index 6c9d77d3dc76df3bd39a0fba37fc25eea28ca522..67ad7a49a2aed617a110086d81ac6458cbe59d65 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -8,4 +8,5 @@ Life Sciences Software List:
 - repositories: redundans-v0.13c
 - repositories: bamtools-2.5.2
 - repositories: flye-2.9
-- repositories: Manta-1.6.0
\ No newline at end of file
+- repositories: Manta-1.6.0
+- repositories: wham-1.8.0
\ No newline at end of file
diff --git a/LifeSciences/wham-1.8.0/build.sh b/LifeSciences/wham-1.8.0/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..904ad6eb144e5c648304f4a14ba27c19b1c89213
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/build.sh
@@ -0,0 +1,63 @@
+#!/bin/bash
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+create_dir()
+{
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p "$path"; else path=$path$(date "+%y%m%d%H%M%S") && mkdir -p "$path"; fi
+    echo "$path"
+}
+
+buildpath=$(create_dir "$1")
+installpath=$(create_dir "$2")
+
+yum install -y m4 environment-modules systemd-devel
+source /etc/profile
+module purge
+
+set -e
+yum install -y cmake zlib zlib-devel xz xz-devel bzip2 bzip2-devel ncurses ncurses-devel curl curl-devel openssl-devel patch
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh "$buildpath" "$installpath"
+module use "$installpath"/bisheng-compiler-2.1.0
+module load "$installpath"/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/bwa-0.7.17.sh "$buildpath" "$installpath"
+module use "$installpath"/bwa-0.7.17
+module load "$installpath"/bwa-0.7.17/bwa_modulefiles
+
+bash $dep_dir/samtools-1.15.1.sh "$buildpath" "$installpath"
+module use "$installpath"/samtools-1.15.1
+module load "$installpath"/samtools-1.15.1/samtools_modulefiles
+
+bash wham-1.8.0.sh "$buildpath" "$installpath"
+
+mkdir -p pkg/wham-1.8.0-hpc && cp -r "$installpath"/* pkg/wham-1.8.0-hpc/
+cat>"pkg/wham-1.8.0-hpc/run.sh"<<EOF
+#!/bin/bash
+sudo yum install -y m4 environment-modules systemd-devel csh time patch libatomic perl-Data-Dumper \\
+autoconf automake libtool numactl binutils valgrind flex wget tar libatomic gcc-c++ git \\
+cmake zlib zlib-devel xz xz-devel bzip2 bzip2-devel ncurses ncurses-devel curl curl-devel openssl-devel
+source /etc/profile &> /dev/null 
+current_dir="\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" && pwd -P)"
+for f in "\${current_dir}"/*; do
+  if [[ -d "\${f}" && -f "\$(ls "\${f}"/*modulefiles 2>&1)" ]]; then
+    module use "\${f}" && module load "\${f}"/*modulefiles
+  fi
+done
+echo -e "\033[1;32;1mwham environment initialization completed.\033[0m"
+
+EOF
+cd pkg/ && tar zcvf wham-1.8.0-hpc.tar.gz wham-1.8.0-hpc
+
+rm -rf "$buildpath" "$installpath"
diff --git a/LifeSciences/wham-1.8.0/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/wham-1.8.0/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..af0c0c656a867d5d95bdfd1c6f5be67dc046f1a0
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,42 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 0 -c -P "$buildpath" https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C "$buildpath" && rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p "$installpath"/bisheng-compiler-2.1.0 && cp -r "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux/* "$installpath"/bisheng-compiler-2.1.0/
+
+cat>"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles"<<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux
diff --git a/LifeSciences/wham-1.8.0/dependency/bwa-0.7.17.sh b/LifeSciences/wham-1.8.0/dependency/bwa-0.7.17.sh
new file mode 100644
index 0000000000000000000000000000000000000000..f671a0a707c59f70988681c85e4e7a3e66d8677e
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/dependency/bwa-0.7.17.sh
@@ -0,0 +1,53 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bwa-0.7.17.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic 
+
+cd "$buildpath"
+wget -t 20 -c https://github.com/lh3/bwa/archive/refs/tags/v0.7.17.tar.gz
+wget -t 20 -c https://github.com/DLTcollab/sse2neon/archive/refs/heads/master.zip
+tar xf v0.7.17.tar.gz && rm -rf v0.7.17.tar.gz
+unzip master.zip && rm -rf master.zip
+cp sse2neon-master/sse2neon.h bwa-0.7.17
+
+cd bwa-0.7.17
+sed -i "s/gcc/clang/" Makefile
+sed -i "29c #include \"sse2neon.h\"" ksw.c
+sed -i "33c extern const uint8_t rle_auxtab[8];" rle.h
+
+make -j$(nproc)
+mkdir -p "$installpath"/bwa-0.7.17
+cp -a ./* "$installpath"/bwa-0.7.17
+
+cat>"$installpath/bwa-0.7.17/bwa_modulefiles"<<EOF
+#%Module1.0
+conflict bwa
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BWA \$pwd
+setenv BWA \$BWA
+prepend-path PATH \$BWA
+EOF
+
+rm -rf "$buildpath"/bwa-0.7.17
diff --git a/LifeSciences/wham-1.8.0/dependency/samtools-1.15.1.sh b/LifeSciences/wham-1.8.0/dependency/samtools-1.15.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..4c4d47b4e0f3301bd7be331ee7cd96b889a94190
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/dependency/samtools-1.15.1.sh
@@ -0,0 +1,45 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash samtools-1.15.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic 
+
+wget -t 20 -c -P "$buildpath" https://github.com/samtools/samtools/releases/download/1.15.1/samtools-1.15.1.tar.bz2
+tar xf "$buildpath"/samtools-1.15.1.tar.bz2 -C "$buildpath" && rm -rf "$buildpath"/samtools-1.15.1.tar.bz2
+cd "$buildpath"/samtools-1.15.1
+
+./configure --prefix="$installpath"/samtools-1.15.1 CC=clang
+make -j$(nproc)
+make install 
+
+cat>"$installpath/samtools-1.15.1/samtools_modulefiles"<<EOF
+#%Module1.0
+conflict samtools
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set SAMTOOLS \$pwd
+setenv SAMTOOLS \$SAMTOOLS
+prepend-path PATH \$SAMTOOLS/bin
+EOF
+
+rm -rf "$buildpath"/samtools-1.15.1
diff --git "a/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..1adc86c7d3d6576b8e3a6fb92ac6352ba946b0b0
Binary files /dev/null and "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..71bfa9dd6df3a39332287c5749349165832456ce
Binary files /dev/null and "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" differ
diff --git "a/LifeSciences/wham-1.8.0/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" "b/LifeSciences/wham-1.8.0/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..7b36b4638c730fa3d3c3edcc3764ad24f613acca
Binary files /dev/null and "b/LifeSciences/wham-1.8.0/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" differ
diff --git a/LifeSciences/wham-1.8.0/wham-1.8.0.patch b/LifeSciences/wham-1.8.0/wham-1.8.0.patch
new file mode 100644
index 0000000000000000000000000000000000000000..bf298e9a6057f9fb511175ad7e465112b3995a0a
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/wham-1.8.0.patch
@@ -0,0 +1,139 @@
+diff -r -u wham-1.8.0/Makefile wham-1.8.0_change/Makefile
+--- wham-1.8.0/Makefile	2015-12-24 08:30:54.000000000 +0800
++++ wham-1.8.0_change/Makefile	2022-07-03 09:45:17.602448034 +0800
+@@ -8,8 +8,8 @@
+ 
+ 
+ 
+-CC=gcc
+-CXX=g++
++CC=clang
++CXX=clang++
+ GIT_VERSION := $(shell git describe --abbrev=4 --dirty --always)
+ CFLAGS= -Wall -DVERSION=\"$(GIT_VERSION)\" -DFAST -std=c++0x
+ INCLUDE=-Isrc/lib -Isrc/bamtools/include -Isrc/bamtools/src -Isrc/ -Isrc/fastahack -Isrc/Complete-Striped-Smith-Waterman-Library/src/ -Isrc/seqan/core/include/ -Isrc/seqan/extras/include
+@@ -27,7 +27,7 @@
+ createBin:
+ 	-mkdir bin
+ bamtools:
+-	cd src/bamtools && mkdir -p build && cd build && cmake .. && make
++	cd src/bamtools && mkdir -p build && cd build && cmake .. -DCMAKE_CXX_COMPILER=clang++ && make
+ libbamtools.a: bamtools
+ 	cp src/bamtools/lib/libbamtools.a .
+ FASTA.o:
+diff -r -u wham-1.8.0/src/bamtools/src/toolkit/bamtools_resolve.cpp wham-1.8.0_change/src/bamtools/src/toolkit/bamtools_resolve.cpp
+--- wham-1.8.0/src/bamtools/src/toolkit/bamtools_resolve.cpp	2022-07-03 09:46:16.235130514 +0800
++++ wham-1.8.0_change/src/bamtools/src/toolkit/bamtools_resolve.cpp	2022-07-03 09:45:01.602255718 +0800
+@@ -412,7 +412,7 @@
+         ReadGroupResolver& resolver = (*rgIter).second;
+ 
+         // store read name with resolver
+-        resolver.ReadNames.insert( make_pair<string,bool>(fields[1], true) ) ;
++        resolver.ReadNames.insert( pair<string,bool>(fields[1], true) ) ;
+     }
+ 
+     // if here, return success
+@@ -609,7 +609,7 @@
+     resolver.IsAmbiguous = ( fields.at(6) == TRUE_KEYWORD );
+ 
+     // store RG entry and return success
+-    readGroups.insert( make_pair<string, ReadGroupResolver>(name, resolver) );
++    readGroups.insert( pair<string, ReadGroupResolver>(name, resolver) );
+     return true;
+ }
+ 
+@@ -1016,7 +1016,7 @@
+         }
+ 
+         // if read name not found, store new entry
+-        else resolver.ReadNames.insert( make_pair<string, bool>(al.Name, isCurrentMateUnique) );
++        else resolver.ReadNames.insert( pair<string, bool>(al.Name, isCurrentMateUnique) );
+     }
+ 
+     // close files
+@@ -1048,7 +1048,7 @@
+     SamReadGroupConstIterator rgEnd  = header.ReadGroups.ConstEnd();
+     for ( ; rgIter != rgEnd; ++rgIter ) {
+         const SamReadGroup& rg = (*rgIter);
+-        m_readGroups.insert( make_pair<string, ReadGroupResolver>(rg.ID, ReadGroupResolver()) );
++        m_readGroups.insert( pair<string, ReadGroupResolver>(rg.ID, ReadGroupResolver()) );
+     }
+ }
+ 
+@@ -1205,7 +1205,7 @@
+     }
+ 
+     // initialize read group map with default (empty name) read group
+-    m_readGroups.insert( make_pair<string, ReadGroupResolver>("", ReadGroupResolver()) );
++    m_readGroups.insert( pair<string, ReadGroupResolver>("", ReadGroupResolver()) );
+ 
+     // init readname filename
+     // uses (adjusted) stats filename if provided (req'd for makeStats, markPairs modes; optional for twoPass)
+diff -r -u wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/main.c wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/main.c
+--- wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/main.c	2022-07-03 09:46:16.219130330 +0800
++++ wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/main.c	2022-07-03 09:45:08.114333990 +0800
+@@ -6,7 +6,7 @@
+ 
+ #include <stdlib.h>
+ #include <stdint.h>
+-#include <emmintrin.h>
++#include "sse2neon.h"
+ #include <zlib.h>
+ #include <stdio.h>
+ #include <time.h>
+diff -r -u wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/Makefile wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/Makefile
+--- wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/Makefile	2022-07-03 09:46:16.219130330 +0800
++++ wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/Makefile	2022-07-03 09:45:27.438566260 +0800
+@@ -1,5 +1,5 @@
+-CC = gcc
+-CXX = g++
++CC = clang
++CXX = clang++
+ CFLAGS := -Wall -O3 -pipe #-pg
+ CXXFLAGS := $(CFLAGS)
+ LOBJS = ssw.o
+diff -r -u wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/ssw.c wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/ssw.c
+--- wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/ssw.c	2022-07-03 09:46:16.219130330 +0800
++++ wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/ssw.c	2022-07-03 09:45:08.890343318 +0800
+@@ -35,7 +35,7 @@
+  *
+  */
+ 
+-#include <emmintrin.h>
++#include "sse2neon.h"
+ #include <stdint.h>
+ #include <stdlib.h>
+ #include <stdio.h>
+diff -r -u wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/ssw.h wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/ssw.h
+--- wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/ssw.h	2022-07-03 09:46:16.219130330 +0800
++++ wham-1.8.0_change/src/Complete-Striped-Smith-Waterman-Library/src/ssw.h	2022-07-03 09:45:08.106333894 +0800
+@@ -14,7 +14,7 @@
+ #include <stdio.h>
+ #include <stdint.h>
+ #include <string.h>
+-#include <emmintrin.h>
++#include "sse2neon.h"
+ 
+ #ifdef __cplusplus
+ extern "C" {
+diff -r -u wham-1.8.0/src/fastahack/Makefile wham-1.8.0_change/src/fastahack/Makefile
+--- wham-1.8.0/src/fastahack/Makefile	2022-07-03 09:46:16.243130606 +0800
++++ wham-1.8.0_change/src/fastahack/Makefile	2022-07-03 09:45:21.658496786 +0800
+@@ -1,4 +1,4 @@
+-CXX=g++
++CXX=clang++
+ CFLAGS=-O3 -D_FILE_OFFSET_BITS=64
+ 
+ fastahack: Fasta.o FastaHack.cpp split.o disorder.o
+diff -r -u wham-1.8.0/src/lib/ssw.c wham-1.8.0_change/src/lib/ssw.c
+--- wham-1.8.0/src/lib/ssw.c	2015-12-24 08:30:54.000000000 +0800
++++ wham-1.8.0_change/src/lib/ssw.c	2022-07-03 09:45:08.098333798 +0800
+@@ -35,7 +35,7 @@
+  *
+  */
+ 
+-#include <emmintrin.h>
++#include "sse2neon.h"
+ #include <stdint.h>
+ #include <stdlib.h>
+ #include <stdio.h>
diff --git a/LifeSciences/wham-1.8.0/wham-1.8.0.sh b/LifeSciences/wham-1.8.0/wham-1.8.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..8ad83dc2836f2a84e3d4dc016d450ba689b64fc8
--- /dev/null
+++ b/LifeSciences/wham-1.8.0/wham-1.8.0.sh
@@ -0,0 +1,63 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash wham-1.8.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum install -y  environment-modules csh time patch libatomic perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex wget
+
+set -e
+wget -t 20 -c -P $buildpath https://github.com/zeeev/wham/archive/refs/tags/1.8.0.zip
+wget -t 40 -c -P $buildpath https://github.com/mengyao/Complete-Striped-Smith-Waterman-Library/archive/8c9933a1685e0ab50c7d8b7926c9068bc0c9d7d2.zip
+wget -t 40 -c -P $buildpath https://github.com/pezmaster31/bamtools/archive/2d7685d2aeedd11c46ad3bd67886d9ed65c30f3e.zip
+wget -t 40 -c -P $buildpath https://github.com/ekg/fastahack/archive/0a8ca3de9239b061839418b306bb6a9072990158.zip
+wget -t 40 -c -P $buildpath https://github.com/seqan/seqan/archive/7f3ca44fbe777f3b637ff57ccc1dcd975cca1661.zip
+
+unzip -d $buildpath "$buildpath"/1.8.0.zip && rm -rf "$buildpath"/1.8.0.zip
+unzip -d $buildpath "$buildpath"/0a8ca3de9239b061839418b306bb6a9072990158.zip && rm -rf "$buildpath"/0a8ca3de9239b061839418b306bb6a9072990158.zip
+unzip -d $buildpath "$buildpath"/2d7685d2aeedd11c46ad3bd67886d9ed65c30f3e.zip && rm -rf "$buildpath"/2d7685d2aeedd11c46ad3bd67886d9ed65c30f3e.zip
+unzip -d $buildpath "$buildpath"/7f3ca44fbe777f3b637ff57ccc1dcd975cca1661.zip && rm -rf "$buildpath"/7f3ca44fbe777f3b637ff57ccc1dcd975cca1661.zip
+unzip -d $buildpath "$buildpath"/8c9933a1685e0ab50c7d8b7926c9068bc0c9d7d2.zip && rm -rf "$buildpath"/8c9933a1685e0ab50c7d8b7926c9068bc0c9d7d2.zip
+
+cp -rf "$buildpath"/Complete-Striped-Smith-Waterman-Library-8c9933a1685e0ab50c7d8b7926c9068bc0c9d7d2/* "$buildpath"/wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/ && rm -rf "$buildpath"/Complete-Striped-Smith-Waterman-Library-8c9933a1685e0ab50c7d8b7926c9068bc0c9d7d2
+cp -rf "$buildpath"/bamtools-2d7685d2aeedd11c46ad3bd67886d9ed65c30f3e/* "$buildpath"/wham-1.8.0/src/bamtools/ && rm -rf "$buildpath"/bamtools-2d7685d2aeedd11c46ad3bd67886d9ed65c30f3e
+cp -rf "$buildpath"/fastahack-0a8ca3de9239b061839418b306bb6a9072990158/* "$buildpath"/wham-1.8.0/src/fastahack/ && rm -rf "$buildpath"/fastahack-0a8ca3de9239b061839418b306bb6a9072990158
+cp -rf "$buildpath"/seqan-7f3ca44fbe777f3b637ff57ccc1dcd975cca1661/* "$buildpath"/wham-1.8.0/src/seqan/ && rm -rf "$buildpath"/seqan-7f3ca44fbe777f3b637ff57ccc1dcd975cca1661
+cp "$buildpath"/sse2neon-master/sse2neon.h "$buildpath"/wham-1.8.0/src/lib/
+cp "$buildpath"/sse2neon-master/sse2neon.h "$buildpath"/wham-1.8.0/src/Complete-Striped-Smith-Waterman-Library/src/ && rm -rf "$buildpath"/sse2neon-master
+cp wham-1.8.0.patch "$buildpath"
+
+cd "$buildpath"
+patch -f -p0 < wham-1.8.0.patch && rm -rf "$buildpath"/wham-1.8.0.patch
+cd wham-1.8.0
+make
+
+mkdir -p "$installpath"/wham-1.8.0 && cp -r "$buildpath"/wham-1.8.0/* "$installpath"/wham-1.8.0
+cat>"$installpath/wham-1.8.0/wham_modulefiles"<<EOF
+#%Module1.0
+conflict wham
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set WHAM \$pwd
+setenv WHAM \$WHAM
+prepend-path PATH \$WHAM/bin
+EOF
+
+rm -rf "$buildpath"/wham-1.8.0
diff --git a/README.md b/README.md
index 18e9e15c1e9932a643fb0c84a2fc2aeb310d2a5e..3016e812f950e956c4178d77b258e48a5df42d80 100644
--- a/README.md
+++ b/README.md
@@ -9,4 +9,5 @@ HPC Software List:
 - repositories: LifeSciences/bamtools-2.5.2
 - repositories: LifeSciences/flye-2.9
 - repositories: LifeSciences/Manta-1.6.0
+- repositories: LifeSciences/wham-1.8.0
 - repositories: ManufacturingSimulation/OpenLB-1.5-0
\ No newline at end of file