diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index be58fcda9c55c61ba9f6cf4d2e006a8b0ba5e83c..0db92da2c5d8f2314e4cdbbae9eca9d5d77b229e 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -12,3 +12,4 @@ Life Sciences Software List:
 - repositories: hmmer-3.3.2
 - repositories: Muscle-5.1
 - repositories: 3d-dna-180922
+- repositories: simpleitk-2.1.1.1
\ No newline at end of file
diff --git a/LifeSciences/SimpleITK-2.1.1.1/SimpleITK-2.1.1.1.sh b/LifeSciences/SimpleITK-2.1.1.1/SimpleITK-2.1.1.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..59e073b242107e8e03b350b1ab3fd94e7ae29e93
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/SimpleITK-2.1.1.1.sh
@@ -0,0 +1,48 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash SimpleITK-2.1.1.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 10 -c -P $buildpath https://github.com/SimpleITK/SimpleITK/releases/download/v2.1.1.1/SimpleITK-2.1.1.1.tar.gz
+tar xf $buildpath/SimpleITK-2.1.1.1.tar.gz -C $installpath && rm -rf $buildpath/SimpleITK-2.1.1.1.tar.gz
+cd $installpath/SimpleITK-2.1.1.1
+mkdir SimpleITK-build
+cd SimpleITK-build
+cmake -DBUILD_EXAMPLES:BOOL=OFF -DWRAP_PYTHON:BOOL=OFF ../SimpleITK-2.1.1.1
+make -j$(nproc)
+make install
+
+cat >$installpath/SimpleITK-2.1.1.1/SimpleITK_modulefiles<<EOF
+#%Module1.0
+conflict simpleitk
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set SIMPLEITK \$pwd
+setenv SIMPLEITK \$SIMPLEITK
+prepend-path LD_LIBRARY_PATH \$SIMPLEITK/lib
+EOF
+
+rm -rf $buildpath/SimpleITK-2.1.1.1
+
+
diff --git a/LifeSciences/SimpleITK-2.1.1.1/build.sh b/LifeSciences/SimpleITK-2.1.1.1/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..a7c3c61a751f2f9714f14cc205dd2934146df6e3
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/build.sh
@@ -0,0 +1,67 @@
+#!/bin/bash
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+create_dir()
+{
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p "$path"; else path=$path$(date "+%y%m%d%H%M%S") && mkdir -p "$path"; fi
+    echo "$path"
+}
+
+buildpath=$(create_dir "$1")
+installpath=$(create_dir "$2")
+
+yum install -y m4 environment-modules systemd-devel
+source /etc/profile
+module purge
+
+set -e
+yum install lua lua-devel gtest gtest-devel python3-numpy -y
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh "$buildpath" "$installpath"
+module use "$installpath"/bisheng-compiler-2.1.0
+module load "$installpath"/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/cmake-3.17.3.sh "$buildpath" "$installpath"
+module use "$installpath"/cmake-3.17.3
+module load "$installpath"/cmake-3.17.3/cmake_modulefiles
+
+bash $dep_dir/ITK-5.2.1.sh "$buildpath" "$installpath"
+module use "$installpath"/ITK-5.2.1
+module load "$installpath"/ITK-5.2.1/ITK_modulefiles
+
+bash $dep_dir/swig-4.0.2.sh "$buildpath" "$installpath"
+module use "$installpath"/swig-4.0.2
+module load "$installpath"/swig-4.0.2/swig_modulefiles
+
+bash SimpleITK-2.1.1.1.sh "$buildpath" "$installpath"
+
+mkdir -p pkg/SimpleITK-2.1.1.1-hpc && cp -r "$installpath"/* pkg/SimpleITK-2.1.1.1-hpc/
+cat>"pkg/wham-1.8.0-hpc/run.sh"<<EOF
+#!/bin/bash
+sudo yum install -y m4 environment-modules systemd-devel csh time patch libatomic perl-Data-Dumper \\
+autoconf automake libtool numactl binutils valgrind flex wget tar libatomic gcc-c++ git \\
+yum install lua lua-devel gtest gtest-devel python3-numpy
+source /etc/profile &> /dev/null 
+current_dir="\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" && pwd -P)"
+for f in "\${current_dir}"/*; do
+  if [[ -d "\${f}" && -f "\$(ls "\${f}"/*modulefiles 2>&1)" ]]; then
+    module use "\${f}" && module load "\${f}"/*modulefiles
+  fi
+done
+echo -e "\033[1;32;1mSimpleITK environment initialization completed.\033[0m"
+
+EOF
+cd pkg/ && tar zcvf SimpleITK-2.1.1.1-hpc.tar.gz SimpleITK-2.1.1.1-hpc
+
+rm -rf "$buildpath" "$installpath"
diff --git a/LifeSciences/SimpleITK-2.1.1.1/dependency/ITK-5.2.1.sh b/LifeSciences/SimpleITK-2.1.1.1/dependency/ITK-5.2.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..b1230febccaa2b84a44cd5f514fd09c6db5c4b38
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/dependency/ITK-5.2.1.sh
@@ -0,0 +1,48 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash ITK-5.2.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 10 -c -P $buildpath https://github.com/InsightSoftwareConsortium/ITK/releases/download/v5.2.1/InsightToolkit-5.2.1.tar.gz
+tar xf $buildpath/InsightToolkit-5.2.1.tar.gz -C $installpath && rm -rf $buildpath/InsightToolkit-5.2.1.tar.gz
+cd $installpath/InsightToolkit-5.2.1
+mkdir build
+cd build
+cmake -D CMAKE_C_COMPILER=clang CMAKE_CXX_COMPILER=clang++  ..
+make -j $(nproc)
+make install
+
+cat >$installpath//ITK-5.2.1/ITK_modulefiles<<EOF
+#%Module1.0
+conflict ITK
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set ITK \$pwd
+setenv ITK \$ITK
+prepend-path PATH \$ITK/InsightToolkit-5.2.1/build/bin
+EOF
+
+rm -rf $buildpath/InsightToolkit-5.2.1
+
+
diff --git a/LifeSciences/SimpleITK-2.1.1.1/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/SimpleITK-2.1.1.1/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..af0c0c656a867d5d95bdfd1c6f5be67dc046f1a0
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,42 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 0 -c -P "$buildpath" https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C "$buildpath" && rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p "$installpath"/bisheng-compiler-2.1.0 && cp -r "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux/* "$installpath"/bisheng-compiler-2.1.0/
+
+cat>"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles"<<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux
diff --git a/LifeSciences/SimpleITK-2.1.1.1/dependency/cmake-3.17.3.sh b/LifeSciences/SimpleITK-2.1.1.1/dependency/cmake-3.17.3.sh
new file mode 100644
index 0000000000000000000000000000000000000000..9972928dea38b58343403f86b7dbb36028d250f1
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/dependency/cmake-3.17.3.sh
@@ -0,0 +1,43 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash cmake-3.17.3.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install wget tar environment-modules libatomic openssl-devel flex bison-devel libxml2 libxml2-devel doxygen libstdc++-static fuse-devel fuse hdf5 hdf5-devel openssl-devel -y
+wget -t 10 -c -P $buildpath https://github.com/Kitware/CMake/releases/download/v3.17.3/cmake-3.17.3.tar.gz
+tar xf $buildpath/cmake-3.17.3.tar.gz -C $buildpath && rm -rf $buildpath/cmake-3.17.3.tar.gz
+cd $buildpath/cmake-3.17.3
+./configure --prefix=$installpath/cmake-3.17.3 CC=clang CXX=clang++ 
+make -j$(nproc) && make install 
+cat >$installpath/cmake-3.17.3/cmake_modulefiles<<EOF
+#%Module1.0
+conflict cmake
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set CMAKE \$pwd
+setenv CMAKE \$CMAKE
+prepend-path PATH \$CMAKE/bin
+EOF
+
+rm -rf $buildpath/cmake-3.17.3
+
+
diff --git a/LifeSciences/SimpleITK-2.1.1.1/dependency/swig-4.0.2.sh b/LifeSciences/SimpleITK-2.1.1.1/dependency/swig-4.0.2.sh
new file mode 100644
index 0000000000000000000000000000000000000000..099dfa459f6849949861e3d1fdcc705fe3cbd512
--- /dev/null
+++ b/LifeSciences/SimpleITK-2.1.1.1/dependency/swig-4.0.2.sh
@@ -0,0 +1,46 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash swig-4.0.2.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 10 -c -P $buildpath https://nchc.dl.sourceforge.net/project/swig/swig/swig-4.0.2/swig-4.0.2.tar.gz
+tar xf $buildpath/swig-4.0.2.tar.gz -C $buildpath && rm -rf $buildpath/swig-4.0.2.tar.gz
+cd $buildpath/swig-4.0.2
+CC=clang CXX=clang++ FC=flang ./configure --prefix=$installpath/SWIG-4.0.2/
+make -j$(nproc)
+make install
+
+cat >$installpath/SWIG-4.0.2/SWIG_modulefiles<<EOF
+#%Module1.0
+conflict ITK
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set SWIG \$pwd
+setenv SWIG \$SWIG
+prepend-path PATH \$SWIG/bin
+EOF
+
+rm -rf $buildpath/swig-4.0.2
+
+
diff --git "a/LifeSciences/SimpleITK-2.1.1.1/doc/SimpleITK-2.1.1.1\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/SimpleITK-2.1.1.1/doc/SimpleITK-2.1.1.1\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
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diff --git "a/LifeSciences/SimpleITK-2.1.1.1/doc/SimpleITK-2.1.1.1\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227 .docx" "b/LifeSciences/SimpleITK-2.1.1.1/doc/SimpleITK-2.1.1.1\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227 .docx"
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diff --git a/README.md b/README.md
index e0f6b168101fc54e4b69d1bf147172fdd5d45aad..fb9219bf049f228c1c4dbfde09ddd20219a17ee4 100644
--- a/README.md
+++ b/README.md
@@ -14,3 +14,4 @@ HPC Software List:
 - repositories: ManufacturingSimulation/SU2-6.0.1
 - repositories: LifeSciences/Muscle-5.1
 - repositories: LifeSciences/3d-dna-180922
+- repositories: LifeSciences/simpleitk-2.1.1.1