diff --git a/LifeSciences/freesurfer-7.2/build.sh b/LifeSciences/freesurfer-7.2/build.sh
index a0810e5ced19fb981ade414b35ddf34610fc829d..772e7312d9e36b0942e474552222ab9e66d96019 100644
--- a/LifeSciences/freesurfer-7.2/build.sh
+++ b/LifeSciences/freesurfer-7.2/build.sh
@@ -41,8 +41,7 @@ yum install lapack-devel lapack-static blas-devel blas-static zlib-devel -y
 yum install libX11-devel libXmu-devel mesa-libGL-devel freeglut-devel libXi-devel -y
 yum install -y python3 python3-numpy libjpeg libtiff giflib gstreamer* libgtk* gtk2-devel libxvidcore* libx264* libgtk-3* gtk3-devel tbb openblas lapack jasper hdf5-devel protobuf
 yum install python-devel python3-devel -y
-pip3 install h5py
-pip3 install numpy
+pip3 install -i https://pypi.tuna.tsinghua.edu.cn/simple h5py numpy
 
 
 bash $dep_dir/petsc-2.3.3.sh $buildpath $installpath
@@ -87,7 +86,7 @@ cat >"pkg/freesurfer-7.2-hpc/run.sh" <<EOF
 yum install bc libatomic environment-modules wget cmake tar perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex gcc-c++ gcc-gfortran git -y
 yum install -y tcsh libgfortran-static make vim-common lapack-devel lapack-static blas-devel blas-static zlib-devel python-devel python3-devel libX11-devel libXmu-devel mesa-libGL-devel freeglut-devel libXi-devel
 yum install qt5-qtquickcontrols qt5-qtdeclarative-devel qt5-qtbase-devel -y
-pip3 install h5py
+pip3 install -i https://pypi.tuna.tsinghua.edu.cn/simple h5py
 source /etc/profile &> /dev/null 
 current_dir=\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" &> /dev/null && pwd)
 for d in \$(ls \$current_dir)
diff --git a/LifeSciences/freesurfer-7.2/dependency/sip-4.18.sh b/LifeSciences/freesurfer-7.2/dependency/sip-4.18.sh
index 2e1bc1c664bbf5d59c275f68bff2cebb670ff2a1..a1730232710e3289cd26065e4162692fd1c28708 100644
--- a/LifeSciences/freesurfer-7.2/dependency/sip-4.18.sh
+++ b/LifeSciences/freesurfer-7.2/dependency/sip-4.18.sh
@@ -25,7 +25,7 @@ if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
 set -e
 yum install qt5-qtquickcontrols qt5-qtdeclarative-devel qt5-qtbase-devel -y
 yum install python-devel python3-devel -y
-pip3 install h5py
+pip3 install -i https://pypi.tuna.tsinghua.edu.cn/simple h5py
 wget -t 40 -c -P $buildpath http://nchc.dl.sourceforge.net/project/pyqt/sip/sip-4.18/sip-4.18.tar.gz
 tar -xzvf $buildpath/sip-4.18.tar.gz -C $buildpath && rm -rf $buildpath/sip-4.18.tar.gz
 cd $buildpath/sip-4.18
diff --git a/LifeSciences/freesurfer-7.2/freesurfer.sh b/LifeSciences/freesurfer-7.2/freesurfer.sh
index 7f1e83938aeaeeec38c1682e912e3847cbb63018..979d62817baf4f549d2d373702b13721a15cb426 100644
--- a/LifeSciences/freesurfer-7.2/freesurfer.sh
+++ b/LifeSciences/freesurfer-7.2/freesurfer.sh
@@ -111,9 +111,10 @@ for file in $(find . -name flags.make); do sed -i 's/-fallow-invalid-boz//g' $fi
 for file in $(find . -name link.txt); do sed -i 's/-fallow-invalid-boz//g' $file; done
 for file in $(find . -name link.txt); do sed -i 's/flang/flang -fno-fortran-main/g' $file; done
 
-sed -i "56i execute_process(COMMAND bash -c \"$installpath/freesurfer/python/bin/python3 -m pip install --upgrade --default-timeout=1000 --disable-pip-version-check $buildpath/tensorflow-2.2.0-cp37-none-linux_aarch64.whl --target=$installpath/freesurfer/python/packages\" RESULT_VARIABLE retcode)" python/cmake_install.cmake
+sed -i "56i execute_process(COMMAND bash -c \"$installpath/freesurfer/python/bin/python3 -m pip install -i https://pypi.tuna.tsinghua.edu.cn/simple --upgrade --default-timeout=1000 --disable-pip-version-check $buildpath/tensorflow-2.2.0-cp37-none-linux_aarch64.whl --target=$installpath/freesurfer/python/packages\" RESULT_VARIABLE retcode)" python/cmake_install.cmake
 sed -i '56s/^/    &/g' python/cmake_install.cmake
-sed -i '57s/--upgrade/--upgrade --default-timeout=1000/g' python/cmake_install.cmake
+sed -i '57s/--upgrade/-i https:\/\/pypi.tuna.tsinghua.edu.cn\/simple --upgrade --default-timeout=1000/g' python/cmake_install.cmake
+sed -i '43s/--upgrade/-i https:\/\/pypi.tuna.tsinghua.edu.cn\/simple --upgrade --default-timeout=1000/g' python/cmake_install.cmake
 make -j$(nproc)
 make install