diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index d3aadd7a731e34a52f0676e2d2dc33797db13888..445fbc7d1a139a9e90429b3f249a5c597ef09b4d 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -1,2 +1,3 @@
 Life Sciences Software List:
 - repositories: xxx
+- repositories: hmmer-3.3.2
diff --git a/LifeSciences/hmmer-3.3.2/build.sh b/LifeSciences/hmmer-3.3.2/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..81712fd20aa834a8ddca1587250856744babc2ad
--- /dev/null
+++ b/LifeSciences/hmmer-3.3.2/build.sh
@@ -0,0 +1,63 @@
+#!/bin/bash
+export LANG="en_US.UTF-8"
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+create_dir()
+{
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p $path; else path=$path`date "+%y%m%d%H%M%S"` && mkdir -p $path; fi
+    echo $path
+}
+
+buildpath=$(create_dir $1)
+installpath=$(create_dir $2)
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum install -y m4 environment-modules systemd-devel
+source /etc/profile
+module purge
+
+set -e
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh $buildpath $installpath
+module use $installpath/bisheng-compiler-2.1.0
+module load $installpath/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/hmpi-1.1.1.sh $buildpath $installpath
+module use $installpath/hmpi-1.1.1
+module load $installpath/hmpi-1.1.1/hmpi_modulefiles
+
+bash $dep_dir/autoconf-2.71.sh $buildpath $installpath
+module use $installpath/autoconf-2.71
+module load $installpath/autoconf-2.71/autoconf_modulefiles
+
+bash hmmer-3.3.2.sh $buildpath $installpath
+
+mkdir -p pkg/hmmer-3.3.2-hpc && cp -r $installpath/* pkg/hmmer-3.3.2-hpc/
+cat>"pkg/hmmer-3.3.2-hpc/run.sh"<<EOF
+#!/bin/bash
+yum install -y m4 environment-modules systemd-devel csh time patch libatomic perl-Data-Dumper \\
+autoconf automake libtool numactl binutils valgrind flex wget tar libatomic gcc-c++ git
+source /etc/profile &> /dev/null
+current_dir=\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" &> /dev/null && pwd)
+for d in \$(ls \$current_dir)
+do
+    [[ ! \$d =~ "hmmer" && ! -f "\$current_dir/\$d" ]] && cd \$current_dir/\$d && module use \$(pwd) && module load \$(pwd)/*modulefiles
+done
+export PATH=\$current_dir/hmmer-3.3.2/bin:\$PATH
+cd \$current_dir
+[[ ! -d "$installpath/hmpi-1.1.1" ]] && mkdir -p $installpath/hmpi-1.1.1 && cp -r \$current_dir/hmpi-1.1.1/* $installpath/hmpi-1.1.1/
+EOF
+cd pkg/ && tar zcvf hmmer-3.3.2-hpc.tar.gz hmmer-3.3.2-hpc
+
+rm -rf $buildpath $installpath
+
diff --git a/LifeSciences/hmmer-3.3.2/dependency/autoconf-2.71.sh b/LifeSciences/hmmer-3.3.2/dependency/autoconf-2.71.sh
new file mode 100644
index 0000000000000000000000000000000000000000..857345fb0155d722674359c1ae6c4f001f3dc052
--- /dev/null
+++ b/LifeSciences/hmmer-3.3.2/dependency/autoconf-2.71.sh
@@ -0,0 +1,47 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash zlib-1.12.11.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules
+
+wget -t 0 -c -P $buildpath http://ftp.gnu.org/gnu/autoconf/autoconf-2.71.tar.gz
+cd $buildpath
+tar -zxvf autoconf-2.71.tar.gz
+cd autoconf-2.71
+./configure --prefix=$installpath/autoconf-2.71
+make && make install
+
+mkdir -p $installpath/autoconf-2.71 && cp -r $buildpath/autoconf-2.71/* $installpath/autoconf-2.71/
+
+cat>"$installpath/autoconf-2.71/autoconf_modulefiles"<<EOF
+#%Module1.0
+conflict autoconf
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set AUTOCONF \$pwd
+setenv AUTOCONF \$AUTOCONF
+prepend-path PATH \$AUTOCONF/bin
+EOF
+
+rm -rf $buildpath/autoconf-2.71
+
diff --git a/LifeSciences/hmmer-3.3.2/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/hmmer-3.3.2/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..81547c757d4ea5048151f67b260345725e005fab
--- /dev/null
+++ b/LifeSciences/hmmer-3.3.2/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,43 @@
+#!/bin/bash
+export LANG="en_US.UTF-8"
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 0 -c -P $buildpath https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C $buildpath && rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p $installpath/bisheng-compiler-2.1.0 && cp -r $buildpath/bisheng-compiler-2.1.0-aarch64-linux/* $installpath/bisheng-compiler-2.1.0/
+
+cat>"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles"<<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux
+
diff --git a/LifeSciences/hmmer-3.3.2/dependency/hmpi-1.1.1.sh b/LifeSciences/hmmer-3.3.2/dependency/hmpi-1.1.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..ec9ce07053d1846c00267962ddcb7464e0644a6c
--- /dev/null
+++ b/LifeSciences/hmmer-3.3.2/dependency/hmpi-1.1.1.sh
@@ -0,0 +1,72 @@
+#!/bin/bash
+export LANG="en_US.UTF-8"
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash hmpi-1.1.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex environment-modules gcc-c++ git
+
+download_pkg()
+{
+    wget -t 0 -c -P $buildpath $1
+    tar xf $buildpath/v1.1.1-huawei.tar.gz -C $buildpath
+    rm -rf $buildpath/v1.1.1-huawei.tar.gz
+}
+
+download_pkg https://github.com/kunpengcompute/hmpi/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/hucx/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/xucg/archive/refs/tags/v1.1.1-huawei.tar.gz
+cp -r $buildpath/xucg-1.1.1-huawei/* $buildpath/hucx-1.1.1-huawei/src/ucg/
+cd $buildpath/hucx-1.1.1-huawei
+git init && ./autogen.sh
+./contrib/configure-opt --prefix=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei --disable-numa CC=clang CXX=clang++ FC=flang
+for file in `find . -name Makefile`;do sed -i "s/-Werror//g" $file;done
+for file in `find . -name Makefile`;do sed -i "s/-implicit-function-declaration//g" $file;done
+make -j$(nproc)
+make -j$(nproc) install
+export PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/bin:$PATH
+export LD_LIBRARY_PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/lib:$LD_LIBRARY_PATH
+export INCLUDE=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/include:$INCLUDE
+cd $buildpath/hmpi-1.1.1-huawei
+./autogen.pl CC=clang CXX=clang++ FC=flang
+./configure --prefix=$installpath/hmpi-1.1.1/hmpi-1.1.1-huawei --with-platform=contrib/platform/mellanox/optimized --enable-mpil-compatibility \
+	--with-ucx=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei CC=clang CXX=clang++ FC=flang
+make -j$(nproc)
+make -j$(nproc) install
+cat>"$installpath/hmpi-1.1.1/hmpi_modulefiles"<<EOF
+#%Module1.0
+conflict hmpi
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set HUCX \$pwd/hucx-1.1.1-huawei
+setenv HUCX \$HUCX
+prepend-path PATH \$HUCX/bin
+prepend-path LD_LIBRARY_PATH \$HUCX/lib
+prepend-path INCLUDE \$HUCX/include
+set HMPI \$pwd/hmpi-1.1.1-huawei
+setenv HMPI \$HMPI
+prepend-path PATH \$HMPI/bin
+prepend-path LD_LIBRARY_PATH \$HMPI/lib
+prepend-path INCLUDE \$HMPI/include
+EOF
+
+rm -rf $buildpath/xucg-1.1.1-huawei $buildpath/hucx-1.1.1-huawei $buildpath/hmpi-1.1.1-huawei
+
diff --git "a/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
new file mode 100644
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Binary files /dev/null and "b/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
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Binary files /dev/null and "b/LifeSciences/hmmer-3.3.2/doc/HMMER-3.3.2\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" differ
diff --git "a/LifeSciences/hmmer-3.3.2/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" "b/LifeSciences/hmmer-3.3.2/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx"
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Binary files /dev/null and "b/LifeSciences/hmmer-3.3.2/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" differ
diff --git a/LifeSciences/hmmer-3.3.2/hmmer-3.3.2.sh b/LifeSciences/hmmer-3.3.2/hmmer-3.3.2.sh
new file mode 100644
index 0000000000000000000000000000000000000000..68e954c2e3b5ead9205c9c39457d8b112f5ef7fb
--- /dev/null
+++ b/LifeSciences/hmmer-3.3.2/hmmer-3.3.2.sh
@@ -0,0 +1,55 @@
+#!/bin/bash
+export LANG="en_US.UTF-8"
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash wrf-4.2.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum install -y  environment-modules csh time patch libatomic perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex wget
+
+set -e
+wget -t 0 -c -P $buildpath https://github.com/EddyRivasLab/hmmer/archive/refs/heads/h3-arm.zip
+unzip $buildpath/h3-arm.zip -d $buildpath
+cd $buildpath/hmmer-h3-arm/
+wget -t 0 -c https://github.com/EddyRivasLab/easel/archive/refs/heads/master.zip
+unzip master.zip
+mv easel-master/ easel/
+autoconf
+export MPICC=mpicc
+export MPICXX=mpicxx
+export MPIFC=mpifort
+
+./configure --prefix=$installpath/hmmer-3.3.2 --enable-mpi --enable-neon CC=$MPICC CXX=$MPICXX FC=$MPIFC F77=$MPIFC
+sed -i 's/esl_FCompare/esl_FCompareNew/g' src/p7_domain.c
+sed -i 's/esl_DCompare/esl_DCompareNew/g' src/p7_domain.c
+sed -i 's/esl_FCompare/esl_FCompareNew/g' src/p7_hit.c
+sed -i 's/esl_DCompare/esl_DCompareNew/g' src/p7_hit.c
+
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/p7_hmm.c
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/p7_trace.c
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/impl_neon/p7_oprofile.c
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/generic_vtrace.c
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/p7_bg.c
+sed -i 's/esl_FCompare_old/esl_FCompare/g' src/p7_gmx.c
+
+sed -i '41 d' src/impl_neon/impl_neon.h
+sed -i '29c static inline float' src/impl_neon/impl_neon.h
+
+make -j$(nproc)
+make -j$(nproc) install
+
+mkdir -p $installpath/hmmer-3.3.2 && cp -r $buildpath/hmmer-h3-arm/* $installpath/hmmer-3.3.2
+
+rm -rf $buildpath/hmmer-3.3.2
+
diff --git a/README.md b/README.md
index 85f84fb3c562de5f1faca4db311e82c79962df5a..67c2394165331da7398da2e4fee2c0659ed8d4f4 100644
--- a/README.md
+++ b/README.md
@@ -1,2 +1,3 @@
 HPC Software List:
 - repositories: MeteorologicalOcean/wrf-4.2
+- repositories: LifeSciences/hmmer-3.3.2