diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index 90d1b60f8abc527b04372def4f0bca509c3fa573..c2382ba849951144a6ff081d33da409b10f5f05f 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -32,3 +32,4 @@ Life Sciences Software List:
 - repositories: SimpleITK-2.1.1.1
 - repositories: figtree-1.4.4
 - repositories: graphmap-0.3.0
+- repositories: wham-1.8.0
diff --git "a/LifeSciences/wham-1.8.0/doc/Devkit\346\212\245\345\221\212/wham-1.8.0Devkit\350\277\201\347\247\273\344\270\216\350\260\203\344\274\230\346\212\245\345\221\212.docx" "b/LifeSciences/wham-1.8.0/doc/Devkit\346\212\245\345\221\212/wham-1.8.0Devkit\350\277\201\347\247\273\344\270\216\350\260\203\344\274\230\346\212\245\345\221\212.docx"
index 940359b444b8e826e2fbf1251f395eb98e577467..8c55f49c15c5309499568966fbdcd324de6f86f2 100644
Binary files "a/LifeSciences/wham-1.8.0/doc/Devkit\346\212\245\345\221\212/wham-1.8.0Devkit\350\277\201\347\247\273\344\270\216\350\260\203\344\274\230\346\212\245\345\221\212.docx" and "b/LifeSciences/wham-1.8.0/doc/Devkit\346\212\245\345\221\212/wham-1.8.0Devkit\350\277\201\347\247\273\344\270\216\350\260\203\344\274\230\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
index d5e5b629d3afea59a221fb9b4013ebbe5a5ac5ce..36c9d1843d773c95c8a439765c3a7b7f65d6bfa1 100644
Binary files "a/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" and "b/LifeSciences/wham-1.8.0/doc/wham-1.8.0\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" differ
diff --git a/LifeSciences/wham-1.8.0/wham-1.8.0.patch b/LifeSciences/wham-1.8.0/wham-1.8.0.patch
index bf298e9a6057f9fb511175ad7e465112b3995a0a..b8cb59af2e8fb724e284ea576e156b359bd5615f 100644
--- a/LifeSciences/wham-1.8.0/wham-1.8.0.patch
+++ b/LifeSciences/wham-1.8.0/wham-1.8.0.patch
@@ -10,7 +10,8 @@ diff -r -u wham-1.8.0/Makefile wham-1.8.0_change/Makefile
 +CC=clang
 +CXX=clang++
  GIT_VERSION := $(shell git describe --abbrev=4 --dirty --always)
- CFLAGS= -Wall -DVERSION=\"$(GIT_VERSION)\" -DFAST -std=c++0x
+-CFLAGS= -Wall -DVERSION=\"$(GIT_VERSION)\" -DFAST -std=c++0x
++CFLAGS= -Wall -DVERSION=\"$(GIT_VERSION)\" -DFAST -std=c++0x -march=armv8.2-a -fsigned-char -ffp-contract=off
  INCLUDE=-Isrc/lib -Isrc/bamtools/include -Isrc/bamtools/src -Isrc/ -Isrc/fastahack -Isrc/Complete-Striped-Smith-Waterman-Library/src/ -Isrc/seqan/core/include/ -Isrc/seqan/extras/include
 @@ -27,7 +27,7 @@
  createBin:
diff --git a/README.md b/README.md
index 8aa825d1492f7f512aa88d583bfeecfef885d60b..ab7b1ecfd58f160521e4797b0080aa194738ed71 100644
--- a/README.md
+++ b/README.md
@@ -36,3 +36,4 @@ HPC Software List:
 - repositories: LifeSciences/SimpleITK-2.1.1.1
 - repositories: LifeSciences/figtree-1.4.4
 - repositories: LifeSciences/graphmap-0.3.0
+- repositories: LifeSciences/wham-1.8.0