diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index 90e4d8d71015b85bb1e3a03c5091ea1911a184da..2fd359dd05ab9f7badc27e23c5994e7fc89541eb 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -3,3 +3,4 @@ Life Sciences Software List:
 - repositories: TRF-4.09.1
 - repositories: genewise-2.4.1
 - repositories: trimmomatic-0.40
+- repositories: RepeatMasker-4.1.2
diff --git a/LifeSciences/RepeatMasker-4.1.2/RepeatMasker-4.1.2.sh b/LifeSciences/RepeatMasker-4.1.2/RepeatMasker-4.1.2.sh
new file mode 100644
index 0000000000000000000000000000000000000000..b0f58972b8aa6efb8441945280702ba2588b4427
--- /dev/null
+++ b/LifeSciences/RepeatMasker-4.1.2/RepeatMasker-4.1.2.sh
@@ -0,0 +1,43 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash wrf-4.2.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+#download src
+wget -t 0 -c -P $buildpath http://www.repeatmasker.org/RepeatMasker/RepeatMasker-4.1.2-p1.tar.gz
+tar -xvf $buildpath/RepeatMasker-4.1.2-p1.tar.gz -C $buildpath && rm -rf $buildpath/RepeatMasker-4.1.2-p1.tar.gz
+#install
+mkdir -p $installpath/RepeatMasker-4.1.2-p1 && cp -r $buildpath/RepeatMasker/* $installpath/RepeatMasker-4.1.2-p1
+
+cat>"$installpath/RepeatMasker-4.1.2-p1/RepeatMasker_modulefiles"<<EOF
+#%Module1.0
+conflict RepeatMasker
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+        set modfile_path [file dirname \$modfile]
+            return \$modfile_path
+    }
+set pwd [getModulefileDir]
+set REPATMASKER \$pwd
+setenv REPATMASKER \$REPATMASKER
+prepend-path PATH \$REPATMASKER
+prepend-path PATH \$REPATMASKER/utils
+EOF
+
+rm -rf $buildpath/RepeatMasker
+
diff --git a/LifeSciences/RepeatMasker-4.1.2/build.sh b/LifeSciences/RepeatMasker-4.1.2/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..78f9f6307a5220affe34a4be939733e56fe2f760
--- /dev/null
+++ b/LifeSciences/RepeatMasker-4.1.2/build.sh
@@ -0,0 +1,64 @@
+#!/bin/bash
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+create_dir()
+{
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p $path; else path=$path`date "+%y%m%d%H%M%S"` && mkdir -p $path; fi
+    echo $path
+}
+
+buildpath=$(create_dir $1)
+installpath=$(create_dir $2)
+
+yum install -y m4 environment-modules systemd-devel
+source /etc/profile
+module purge
+
+set -e
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh $buildpath $installpath
+module use $installpath/bisheng-compiler-2.1.0
+module load $installpath/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/rmblast-2.13.0.sh $buildpath $installpath
+module use $installpath/rmblast-2.13.0
+module load $installpath/rmblast-2.13.0/rmblast_modulefiles
+
+bash $dep_dir/trf-4.09.1.sh $buildpath $installpath
+module use $installpath/trf-4.09.1
+module load $installpath/trf-4.09.1/trf_modulefiles
+
+bash RepeatMasker-4.1.2.sh $buildpath $installpath
+
+mkdir -p pkg/RepeatMasker-4.1.2 && cp -r $installpath/* pkg/RepeatMasker-4.1.2/
+cat>"pkg/RepeatMasker-4.1.2/run.sh"<<EOF
+#!/bin/bash
+yum install -y environment-modules perl python3-h5py \\
+source /etc/profile &> /dev/null 
+current_dir=\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" &> /dev/null && pwd)
+for d in \$(ls \$current_dir)
+do
+    [[ ! \$d =~ "RepeatMasker" && ! -f "\$current_dir/\$d" ]] && cd \$current_dir/\$d && module use \$(pwd) && module load \$(pwd)/*modulefiles
+done
+cd \$current_dir/RepeatMasker-4.1.2-p1
+perl ./configure -libdir \$current_dir/RepeatMasker-4.1.2-p1/Libraries \
+ -rmblast_dir \$current_dir/rmblast-2.13.0/bin \
+ -trf_prgm \$current_dir/trf-4.09.1/bin/trf \
+ -default_search_engine rmblast
+cd \$current_dir
+EOF
+cd pkg/ && tar zcvf RepeatMasker-4.1.2.tar.gz RepeatMasker-4.1.2
+
+rm -rf $buildpath $installpath
+
diff --git a/LifeSciences/RepeatMasker-4.1.2/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/RepeatMasker-4.1.2/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..a53069995751e081370ff3e2559fbc3b2dfd3f4c
--- /dev/null
+++ b/LifeSciences/RepeatMasker-4.1.2/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,43 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic
+
+wget -t 0 -c -P $buildpath https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C $buildpath && rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p $installpath/bisheng-compiler-2.1.0 && cp -r $buildpath/bisheng-compiler-2.1.0-aarch64-linux/* $installpath/bisheng-compiler-2.1.0/
+
+cat>"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles"<<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux
+
diff --git a/LifeSciences/RepeatMasker-4.1.2/dependency/rmblast-2.13.0.sh b/LifeSciences/RepeatMasker-4.1.2/dependency/rmblast-2.13.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..3c05753c8953eece4525c69fdfb4b2017413431a
--- /dev/null
+++ b/LifeSciences/RepeatMasker-4.1.2/dependency/rmblast-2.13.0.sh
@@ -0,0 +1,51 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash rmblast.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar patch environment-modules
+
+#download ncbi-blast+
+wget -t 0 -c -P $buildpath https://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/2.13.0/ncbi-blast-2.13.0+-src.tar.gz
+tar -xzvf $buildpath/ncbi-blast-2.13.0+-src.tar.gz -C $buildpath && rm -rf $buildpath/ncbi-blast-2.13.0+-src.tar.gz
+#download patch for rmblast
+wget -t 0 -c -P $buildpath http://www.repeatmasker.org/isb-2.10.0+-rmblast.patch.gz
+gunzip $buildpath/isb-2.10.0+-rmblast.patch.gz
+#build rmblast
+cd $buildpath/ncbi-blast-2.13.0+-src
+patch -p1 < ../isb-2.10.0+-rmblast.patch
+cd c++
+CC=clang CXX=clang++ ./configure --with-mt --without-debug --without-krb5 --without-openssl --with-projects=scripts/projects/rmblastn/project.lst --prefix=$installpath/rmblast-2.13.0
+make -j$(nproc) && make install
+
+cat>"$installpath/rmblast-2.13.0/rmblast_modulefiles"<<EOF
+#%Module1.0
+conflict rmblast
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+        set modfile_path [file dirname \$modfile]
+            return \$modfile_path
+    }
+set pwd [getModulefileDir]
+set RMBLAST \$pwd
+setenv RMBLAST \$RMBLAST
+prepend-path PATH \$RMBLAST/bin
+EOF
+
+rm -rf $buildpath/ncbi-blast-2.13.0+-src
+
diff --git a/LifeSciences/RepeatMasker-4.1.2/dependency/trf-4.09.1.sh b/LifeSciences/RepeatMasker-4.1.2/dependency/trf-4.09.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..774aa8de7ba02806c0a0ba84bd820b94482645b0
--- /dev/null
+++ b/LifeSciences/RepeatMasker-4.1.2/dependency/trf-4.09.1.sh
@@ -0,0 +1,46 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash trf.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules
+
+wget -t 0 -c -P $buildpath https://github.com/Benson-Genomics-Lab/TRF/archive/refs/tags/v4.09.1.tar.gz -O $buildpath/trf-4.09.1.tar.gz
+tar -xzvf $buildpath/trf-4.09.1.tar.gz -C $buildpath && rm -rf $buildpath/trf-4.09.1.tar.gz
+
+cd $buildpath/TRF-4.09.1
+mkdir build && cd build
+CC=clang CXX=clang++ FC=flang F77=flang F90=flang ../configure --prefix=$installpath/trf-4.09.1
+make -j$(nproc) && make install
+
+cat>"$installpath/trf-4.09.1/trf_modulefiles"<<EOF
+#%Module1.0
+conflict trf
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+        set modfile_path [file dirname \$modfile]
+            return \$modfile_path
+    }
+set pwd [getModulefileDir]
+set TRF \$pwd
+setenv TRF \$TRF
+prepend-path PATH \$TRF/bin
+EOF
+
+rm -rf $buildpath/ncbi-blast-2.13.0+-src
+
diff --git "a/LifeSciences/RepeatMasker-4.1.2/doc/RepeatMasker-4.1.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/RepeatMasker-4.1.2/doc/RepeatMasker-4.1.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
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Binary files /dev/null and "b/LifeSciences/RepeatMasker-4.1.2/doc/RepeatMasker-4.1.2\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/RepeatMasker-4.1.2/doc/RepeatMasker-4.1.2\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/RepeatMasker-4.1.2/doc/RepeatMasker-4.1.2\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
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diff --git "a/LifeSciences/RepeatMasker-4.1.2/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" "b/LifeSciences/RepeatMasker-4.1.2/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx"
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diff --git a/README.md b/README.md
index 9b05362c3146f41fdf194d8451d6904139f1a2b7..944cbe0fc4c16943d0b48ee82939769317c4b703 100644
--- a/README.md
+++ b/README.md
@@ -2,4 +2,5 @@ HPC Software List:
 - repositories: MeteorologicalOcean/wrf-4.2
 - repositories: LifeSciences/TRF-4.09.1
 - repositories: LifeSciences/genewise-2.4.1
-- repositories: LifeSciences/trimmomatic-0.40
\ No newline at end of file
+- repositories: LifeSciences/trimmomatic-0.40
+- repositories: LifeSciences/RepeatMasker-4.1.2