diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index 0fbae3f8c71f4f843628c6f1469a0b5e2d7ead3a..c5841db879bf3efec9c9b08b41fe349b1b0ceaff 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -6,4 +6,5 @@ Life Sciences Software List:
 - repositories: RepeatMasker-4.1.2
 - repositories: eigensoft-7.2.1
 - repositories: redundans-v0.13c
-- repositories: bamtools-2.5.2
\ No newline at end of file
+- repositories: bamtools-2.5.2
+- repositories: amber-20
\ No newline at end of file
diff --git a/LifeSciences/amber-20/amber20.sh b/LifeSciences/amber-20/amber20.sh
new file mode 100644
index 0000000000000000000000000000000000000000..7836d11330f9b796c8e3ce9cf294095cecc1ee95
--- /dev/null
+++ b/LifeSciences/amber-20/amber20.sh
@@ -0,0 +1,53 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash amber-20.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum -y install  cmake boost bzip2 bzip2-devel bison flex libXt-devel libXext-devel libX11-devel libICE-devel libSM-devel 
+set -e
+wget -t 0 -c "https://ambermd.org/cgi-bin/AmberTools21-get.pl?Name=test&Institution=test&City=test&State=ON&Country=AI" -O $buildpath/AmberTools21.tar.bz2
+
+tar -xvf $buildpath/AmberTools21.tar.bz2 -C $buildpath && rm -rf $buildpath/AmberTools21.tar.bz2
+
+cp cmake.defaults.patch $buildpath/amber20_src
+
+cd $buildpath/amber20_src
+
+./update_amber --update
+patch -p2 < ./cmake.defaults.patch
+cd build/
+export CMAKE_PREFIX_PATH=$installpath/openblas
+FLAGS="-mcpu=tsv110  -I$installpath/hmpi-1.1.1/hmpi-1.1.1-huawei/include"
+cmake .. \
+    -DCMAKE_INSTALL_PREFIX=$installpath/amber20 \
+    -DCOMPILER=AUTO \
+    -DCMAKE_C_FLAGS="$FLAGS"  \
+    -DFORCE_EXTERNAL_LIBS=blas \
+    -DCMAKE_CXX_FLAGS="$FLAGS"  \
+    -DCMAKE_Fortran_FLAGS="$FLAGS"  \
+    -DCMAKE_C_COMPILER=clang -DCMAKE_CXX_COMPILER=clang++ -DCMAKE_Fortran_COMPILER=flang \
+    -DMPI=TRUE  -DCUDA=FALSE  -DOPENMP=TRUE -DINSTALL_TESTS=TRUE   \
+    -DDOWNLOAD_MINICONDA=FALSE -DMINICONDA_USE_PY3=FALSE
+
+
+
+sed -i "s/-o CMakeFiles\/cifparse.dir\/cifparse.c.o/-fcommon  -o CMakeFiles\/cifparse.dir\/cifparse.c.o/g" AmberTools/src/cifparse/CMakeFiles/cifparse.dir/build.make
+sed -i "s/-o CMakeFiles\/cifparse.dir\/cifp.tab.c.o/-fcommon  -o CMakeFiles\/cifparse.dir\/cifp.tab.c.o/g" AmberTools/src/cifparse/CMakeFiles/cifparse.dir/build.make
+make -j 8 
+make -j install
+echo './sander-16.0-py3.8-linux-aarch64.egg' >> $installpath/amber20/lib/python3.8/site-packages/easy-install.pth
+echo './ParmEd-3.4.1-py3.8-linux-aarch64.egg' >> $installpath/amber20/lib/python3.8/site-packages/easy-install.pth
+rm -rf $buildpath/amber20_src
diff --git a/LifeSciences/amber-20/build.sh b/LifeSciences/amber-20/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..005466ea707b4c3a4015cada56210b9e2ded284a
--- /dev/null
+++ b/LifeSciences/amber-20/build.sh
@@ -0,0 +1,66 @@
+#!/bin/bash
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+create_dir()
+{
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p $path; else path=$path`date "+%y%m%d%H%M%S"` && mkdir -p $path; fi
+    echo $path
+}
+
+buildpath=$(create_dir $1)
+installpath=$(create_dir $2)
+
+yum install -y m4 environment-modules systemd-devel  --nogpgcheck
+source /etc/profile
+module purge
+
+set -e
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh $buildpath $installpath
+module use $installpath/bisheng-compiler-2.1.0
+module load $installpath/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/hmpi-1.1.1.sh $buildpath $installpath
+module use $installpath/hmpi-1.1.1
+module load $installpath/hmpi-1.1.1/hmpi_modulefiles
+
+bash $dep_dir/miniconda-py38_4.11.0-devel.sh $buildpath $installpath
+module use $installpath/miniconda3
+module load $installpath/miniconda3/miniconda_py38_modulefiles
+
+bash $dep_dir/openblas-0.3.18.sh $buildpath $installpath
+bash $dep_dir/lapack-3.8.0.sh $buildpath $installpath
+module use $installpath/openblas
+module load $installpath/openblas/OpenBLAS-0.3.18_modulefiles
+
+bash amber20.sh  $buildpath $installpath
+
+mkdir -p pkg/amber-20-hpc && cp -r $installpath/* pkg/amber-20-hpc/
+cat>"pkg/amber-20-hpc/run.sh"<<EOF
+#!/bin/bash
+yum install -y m4 environment-modules systemd-devel cmake csh time patch libatomic perl-Data-Dumper \\
+autoconf automake libtool numactl binutils valgrind flex wget tar libatomic gcc-c++ git bison bzip2 bzip2-devel libXt-devel libXext-devel libX11-devel libICE-devel libSM-devel
+source /etc/profile &> /dev/null 
+current_dir=\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" &> /dev/null && pwd)
+source \$current_dir/amber20/amber.sh
+for d in \$(ls \$current_dir)
+do
+    [[ ! \$d =~ "amber" && ! -f "\$current_dir/\$d" ]] && cd \$current_dir/\$d && module use \$(pwd) && module load \$(pwd)/*modulefiles
+done
+cd \$current_dir
+[[ ! -d "$installpath/hmpi-1.1.1" ]] && mkdir -p $installpath/hmpi-1.1.1 && cp -r \$current_dir/hmpi-1.1.1/* $installpath/hmpi-1.1.1/
+EOF
+cd pkg/ && tar zcvf amber-20-hpc.tar.gz amber-20-hpc
+
+rm -rf $buildpath $installpath
diff --git a/LifeSciences/amber-20/cmake.defaults.patch b/LifeSciences/amber-20/cmake.defaults.patch
new file mode 100644
index 0000000000000000000000000000000000000000..067035e8b7ca4819c66dea3aa6756c2760f9397a
--- /dev/null
+++ b/LifeSciences/amber-20/cmake.defaults.patch
@@ -0,0 +1,64 @@
+diff -Nur modify/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp base/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp
+--- modify/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp	2018-06-18 22:24:05.000000000 +0800
++++ base/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp	2022-04-11 20:38:28.235163871 +0800
+@@ -19,7 +19,7 @@
+ 
+ #include "pdb++.h"
+ 
+-extern "C" {
++//extern "C" {
+ #ifdef OLD_STD_HDRS
+ #include <string.h>
+ #else
+@@ -27,7 +27,7 @@
+ using std::memset;
+ using std::memcmp;
+ #endif
+-}
++//}
+ 
+ PDB::PDB()
+ {
+diff -Nur modify/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp base/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp
+--- modify/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp	2018-06-18 22:24:05.000000000 +0800
++++ base/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp	2022-04-11 20:38:47.039378191 +0800
+@@ -20,7 +20,7 @@
+ //
+ 
+ # include	"pdb++.h"
+-extern "C" {
++//extern "C" {
+ #ifdef OLD_STD_HDRS
+ #include <ctype.h>
+ #include <string.h>
+@@ -30,7 +30,7 @@
+ using std::islower;
+ using std::toupper;
+ #endif
+-}
++//}
+ #if defined(__DECCXX_VER) || defined(_MSC_VER)
+ #define NEEDSTRCASECMP
+ #endif
+diff -Nur modify/amber20_src/AmberTools/src/sebomd/se_etimer.F base/amber20_src/AmberTools/src/sebomd/se_etimer.F
+--- modify/amber20_src/AmberTools/src/sebomd/se_etimer.F	2018-08-15 19:33:54.000000000 +0800
++++ base/amber20_src/AmberTools/src/sebomd/se_etimer.F	2022-04-11 20:38:06.450915586 +0800
+@@ -6,7 +6,7 @@
+ #ifdef MPI
+ #include "mpif.h"
+ #endif
+-
++      INTEGER :: mclock
+       double precision t
+
+       double precision tnow, t0
+@@ -24,7 +24,7 @@
+ #     if (__GNUC__ == 4 && __GNUC_MINOR__ <= 1)
+       tnow = second()
+ #     else
+-      tnow = 0.01*mclock()
++      tnow = 0.01*mclock()  !gfortran
+ #     endif
+ #  endif
+ #endif
+
diff --git a/LifeSciences/amber-20/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/amber-20/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..1254ea4f78d28503a7e41da46946345f803752b3
--- /dev/null
+++ b/LifeSciences/amber-20/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,42 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules libatomic --nogpgcheck
+
+wget -t 0 -c -P $buildpath https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C $buildpath && rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p $installpath/bisheng-compiler-2.1.0 && cp -r $buildpath/bisheng-compiler-2.1.0-aarch64-linux/* $installpath/bisheng-compiler-2.1.0/
+
+cat>"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles"<<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf $buildpath/bisheng-compiler-2.1.0-aarch64-linux
diff --git a/LifeSciences/amber-20/dependency/hmpi-1.1.1.sh b/LifeSciences/amber-20/dependency/hmpi-1.1.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..bd285937ab7d7b094e35eb709eb5ed55f6b95a50
--- /dev/null
+++ b/LifeSciences/amber-20/dependency/hmpi-1.1.1.sh
@@ -0,0 +1,72 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash hmpi-1.1.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] &&  echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] &&  echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex environment-modules gcc-c++ git --nogpgcheck
+
+download_pkg()
+{
+    wget -t 0 -c -P $buildpath $1
+    tar xf $buildpath/v1.1.1-huawei.tar.gz -C $buildpath
+    rm -rf $buildpath/v1.1.1-huawei.tar.gz
+}
+
+download_pkg https://github.com/kunpengcompute/hmpi/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/hucx/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/xucg/archive/refs/tags/v1.1.1-huawei.tar.gz
+cp -r $buildpath/xucg-1.1.1-huawei/* $buildpath/hucx-1.1.1-huawei/src/ucg/
+cd $buildpath/hucx-1.1.1-huawei
+git init && ./autogen.sh
+./contrib/configure-opt --prefix=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei --disable-numa CC=clang CXX=clang++ FC=flang
+for file in `find . -name Makefile`;do sed -i "s/-Werror//g" $file;done
+for file in `find . -name Makefile`;do sed -i "s/-implicit-function-declaration//g" $file;done
+make -j$(nproc)
+make -j$(nproc) install
+export PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/bin:$PATH
+export LD_LIBRARY_PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/lib:$LD_LIBRARY_PATH
+export INCLUDE=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/include:$INCLUDE
+cd $buildpath/hmpi-1.1.1-huawei
+./autogen.pl CC=clang CXX=clang++ FC=flang
+./configure --prefix=$installpath/hmpi-1.1.1/hmpi-1.1.1-huawei --with-platform=contrib/platform/mellanox/optimized --enable-mpil-compatibility \
+	--with-ucx=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei CC=clang CXX=clang++ FC=flang
+make -j$(nproc)
+make -j$(nproc) install
+cat>"$installpath/hmpi-1.1.1/hmpi_modulefiles"<<EOF
+#%Module1.0
+conflict hmpi
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set HUCX \$pwd/hucx-1.1.1-huawei
+setenv HUCX \$HUCX
+prepend-path PATH \$HUCX/bin
+prepend-path LD_LIBRARY_PATH \$HUCX/lib
+prepend-path INCLUDE \$HUCX/include
+set HMPI \$pwd/hmpi-1.1.1-huawei
+setenv HMPI \$HMPI
+prepend-path PATH \$HMPI/bin
+prepend-path LD_LIBRARY_PATH \$HMPI/lib
+prepend-path INCLUDE \$HMPI/include
+EOF
+
+rm -rf $buildpath/xucg-1.1.1-huawei $buildpath/hucx-1.1.1-huawei $buildpath/hmpi-1.1.1-huawei 
+
diff --git a/LifeSciences/amber-20/dependency/lapack-3.8.0.sh b/LifeSciences/amber-20/dependency/lapack-3.8.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..867d6bf78b73cb0ebc3bd98befe64be86bb2df35
--- /dev/null
+++ b/LifeSciences/amber-20/dependency/lapack-3.8.0.sh
@@ -0,0 +1,54 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./lapack-0.3.18.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then echo "请输入正确的构建路径"; exit 1; fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then echo "请输入正确的安装路径"; exit 1; fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 0 -c -P $buildpath http://www.netlib.org/lapack/lapack-3.8.0.tar.gz 
+tar xf $buildpath/lapack-3.8.0.tar.gz -C $buildpath && rm -rf $buildpath/lapack-3.8.0.tar.gz
+cd $buildpath/lapack-3.8.0
+sed -i '1i\                 REAL Function etime(time)' INSTALL/second_INT_ETIME.f
+sed -i '2i\                  REAL time(2)' INSTALL/second_INT_ETIME.f
+sed -i '3i\                  Call Cpu_Time(etime)' INSTALL/second_INT_ETIME.f
+sed -i '4i\                  time(1) = etime' INSTALL/second_INT_ETIME.f
+sed -i '5i\                  time(2) = 0' INSTALL/second_INT_ETIME.f
+sed -i '6i\                 End Function' INSTALL/second_INT_ETIME.f
+sed -i 's/REAL               ETIME//g' INSTALL/second_INT_ETIME.f
+sed -i 's/INTRINSIC          ETIME//g' INSTALL/second_INT_ETIME.f
+sed -i 's/T1 = ETIME( TARRAY )/T1 = etime( TARRAY )/g' INSTALL/second_INT_ETIME.f
+
+sed -i '1i\                 REAL Function etime(time)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '2i\                  REAL time(2)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '3i\                  Call Cpu_Time(etime)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '4i\                  time(1) = etime' INSTALL/dsecnd_INT_ETIME.f
+sed -i '5i\                  time(2) = 0' INSTALL/dsecnd_INT_ETIME.f
+sed -i '6i\                 End Function' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/REAL               ETIME//g' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/INTRINSIC          ETIME//g' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/T1 = ETIME( TARRAY )/T1 = etime( TARRAY )/g' INSTALL/dsecnd_INT_ETIME.f
+
+cp make.inc.example make.inc
+sed -i 's/gcc/clang/g' make.inc
+sed -i 's/gfortran/flang/g' make.inc
+sed -i 's/librefblas.a/libblas.a/g' make.inc
+
+make -j $(nproc)
+cp *.a $installpath/openblas/lib
+
+
+rm -rf $buildpath/lapack-3.8.0
+
diff --git a/LifeSciences/amber-20/dependency/miniconda-py38_4.11.0-devel.sh b/LifeSciences/amber-20/dependency/miniconda-py38_4.11.0-devel.sh
new file mode 100644
index 0000000000000000000000000000000000000000..9d50d0998eeb2e2f3286845229fd0b3edd143aba
--- /dev/null
+++ b/LifeSciences/amber-20/dependency/miniconda-py38_4.11.0-devel.sh
@@ -0,0 +1,45 @@
+#!/bin/bash
+
+
+### 使用Miniconda3来安装python依赖
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./miniconda-py38_4.11.0-devel.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then echo "请输入正确的构建路径"; exit 1; fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then echo "请输入正确的安装路径"; exit 1; fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 0 -c -P $buildpath https://repo.anaconda.com/miniconda/Miniconda3-py38_4.11.0-Linux-aarch64.sh
+
+sh $buildpath/Miniconda3-py38_4.11.0-Linux-aarch64.sh -b -p $installpath/miniconda3
+
+$installpath/miniconda3/condabin/conda install -y numpy scipy matplotlib setuptools
+$installpath/miniconda3/bin/pip3 install mpi4py
+
+cat>"$installpath/miniconda3/miniconda_py38_modulefiles"<<EOF
+#%Module1.0
+conflict miniconda_py38
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set MINICONDA_PY38 \$pwd
+setenv MINICONDA_PY38 \$MINICONDA_PY38
+prepend-path PATH \$MINICONDA_PY38/bin
+EOF
+
+rm -rf $buildpath/Miniconda3-py38_4.11.0-Linux-aarch64.sh
diff --git a/LifeSciences/amber-20/dependency/openblas-0.3.18.sh b/LifeSciences/amber-20/dependency/openblas-0.3.18.sh
new file mode 100644
index 0000000000000000000000000000000000000000..44826552201db70a51ff0b533caf20684ce66bf6
--- /dev/null
+++ b/LifeSciences/amber-20/dependency/openblas-0.3.18.sh
@@ -0,0 +1,43 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./openblas-0.3.18.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then echo "请输入正确的构建路径"; exit 1; fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then echo "请输入正确的安装路径"; exit 1; fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 0 -c -P $buildpath https://github.com/xianyi/OpenBLAS/releases/download/v0.3.18/OpenBLAS-0.3.18.tar.gz
+tar xf $buildpath/OpenBLAS-0.3.18.tar.gz -C $buildpath && rm -rf $buildpath/OpenBLAS-0.3.18.tar.gz
+cd $buildpath/OpenBLAS-0.3.18
+
+CC=clang CXX=clang++ FC=flang \
+make -j$(nproc) && make -j$(nproc)  PREFIX=$installpath/openblas install
+
+
+cat>"$installpath/openblas/OpenBLAS-0.3.18_modulefiles"<<EOF
+#%Module1.0
+conflict OpenBLAS
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set OpenBLAS \$pwd
+setenv OpenBLAS \$OpenBLAS
+prepend-path LD_LIBRARY_PATH \$OpenBLAS/lib
+EOF
+
+rm -rf $buildpath/OpenBLAS-0.3.18
diff --git "a/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..195458b2a1c1dde4989d40519ab76beee9a8a900
Binary files /dev/null and "b/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
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index 0000000000000000000000000000000000000000..8d1bf602ea78f2ba30f30f4ad7602457e4443d7b
Binary files /dev/null and "b/LifeSciences/amber-20/doc/Amber-20\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" differ
diff --git "a/LifeSciences/amber-20/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" "b/LifeSciences/amber-20/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..35bfa2ef3f80cddc611325e64621c5d9948caf8f
Binary files /dev/null and "b/LifeSciences/amber-20/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" differ
diff --git a/README.md b/README.md
index f76b5597fa1983b4b6fac5c03c296f27be507f33..5c5a1c64b5140ff89eb951ec25116712fa6c97f0 100644
--- a/README.md
+++ b/README.md
@@ -6,4 +6,5 @@ HPC Software List:
 - repositories: LifeSciences/RepeatMasker-4.1.2
 - repositories: LifeSciences/eigensoft-7.2.1
 - repositories: LifeSciences/redundans-v0.13c
-- repositories: LifeSciences/bamtools-2.5.2
\ No newline at end of file
+- repositories: LifeSciences/bamtools-2.5.2
+- repositories: LifeSciences/amber-20
\ No newline at end of file