diff --git a/LifeSciences/README.md b/LifeSciences/README.md
index 4cd10237658beb349546b28d0bb95f3b42dc0607..cffd101b6aec3700ed6736f799b17ef9502f3b25 100644
--- a/LifeSciences/README.md
+++ b/LifeSciences/README.md
@@ -14,4 +14,4 @@ Life Sciences Software List:
 - repositories: Muscle-5.1
 - repositories: 3d-dna-180922
 - repositories: featureCounts-2.0.3
-
+- repositories: ambertools-21
diff --git a/LifeSciences/ambertools-21/ambertools-21.sh b/LifeSciences/ambertools-21/ambertools-21.sh
new file mode 100644
index 0000000000000000000000000000000000000000..11e2b4304c2a6d27089efe9522edd4c1abbbd760
--- /dev/null
+++ b/LifeSciences/ambertools-21/ambertools-21.sh
@@ -0,0 +1,54 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash ambertools-21.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] && echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] && echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+yum -y install cmake time boost bzip2 bzip2-devel bison flex libXt-devel libXext-devel tcsh make \
+    which flex bison patch bc \
+    perl perl-ExtUtils-MakeMaker util-linux wget \
+    bzip2 bzip2-devel zlib-devel tar
+set -e
+wget -t 50 -c "https://ambermd.org/cgi-bin/AmberTools21-get.pl?Name=test&Institution=test&City=test&State=ON&Country=AI" -O "$buildpath"/AmberTools21.tar.bz2
+
+tar -xvf "$buildpath"/AmberTools21.tar.bz2 -C "$buildpath" && rm -rf "$buildpath"/AmberTools21.tar.bz2
+
+cp cmake.defaults.patch "$buildpath"/amber20_src
+
+cd "$buildpath"/amber20_src
+
+./update_amber --update
+patch -p2 <./cmake.defaults.patch
+cd build/
+export CMAKE_PREFIX_PATH=$installpath/openblas
+FLAGS="-mcpu=tsv110  -I$installpath/hmpi-1.1.1/hmpi-1.1.1-huawei/include"
+cmake .. \
+    -DCMAKE_INSTALL_PREFIX="$installpath"/ambertools21 \
+    -DCOMPILER=AUTO \
+    -DCMAKE_C_FLAGS="$FLAGS" \
+    -DFORCE_EXTERNAL_LIBS=blas \
+    -DCMAKE_CXX_FLAGS="$FLAGS" \
+    -DCMAKE_Fortran_FLAGS="$FLAGS" \
+    -DCMAKE_C_COMPILER=clang -DCMAKE_CXX_COMPILER=clang++ -DCMAKE_Fortran_COMPILER=flang \
+    -DMPI=TRUE -DCUDA=FALSE -DOPENMP=TRUE -DINSTALL_TESTS=TRUE \
+    -DDOWNLOAD_MINICONDA=FALSE -DMINICONDA_USE_PY3=FALSE
+
+sed -i "s/-o CMakeFiles\/cifparse.dir\/cifparse.c.o/-fcommon  -o CMakeFiles\/cifparse.dir\/cifparse.c.o/g" AmberTools/src/cifparse/CMakeFiles/cifparse.dir/build.make
+sed -i "s/-o CMakeFiles\/cifparse.dir\/cifp.tab.c.o/-fcommon  -o CMakeFiles\/cifparse.dir\/cifp.tab.c.o/g" AmberTools/src/cifparse/CMakeFiles/cifparse.dir/build.make
+make -j 8
+make -j install
+echo './sander-16.0-py3.8-linux-aarch64.egg' >>"$installpath"/ambertools21/lib/python3.8/site-packages/easy-install.pth
+echo './ParmEd-3.4.1-py3.8-linux-aarch64.egg' >>"$installpath"/ambertools21/lib/python3.8/site-packages/easy-install.pth
+rm -rf "$buildpath"/amber20_src
diff --git a/LifeSciences/ambertools-21/build.sh b/LifeSciences/ambertools-21/build.sh
new file mode 100644
index 0000000000000000000000000000000000000000..8fff6d1e8f3a87f2822207657decc199308430c0
--- /dev/null
+++ b/LifeSciences/ambertools-21/build.sh
@@ -0,0 +1,65 @@
+#!/bin/bash
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash build.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || "$1" = "/" ]] && echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || "$2" = "/" ]] && echo "请输入正确的安装路径" && exit 1
+
+create_dir() {
+    local path=$1
+    [[ "$path" =~ .*/$ ]] && path=${path%/*}
+    if [[ ! -d "$path" && ! -f "$path" ]]; then mkdir -p "$path"; else path=$path$(date "+%y%m%d%H%M%S") && mkdir -p "$path"; fi
+    echo "$path"
+}
+
+buildpath=$(create_dir "$1")
+installpath=$(create_dir "$2")
+
+yum install -y m4 environment-modules systemd-devel --nogpgcheck
+source /etc/profile
+module purge
+
+set -e
+dep_dir="dependency"
+bash $dep_dir/bisheng-compiler-2.1.0.sh "$buildpath" "$installpath"
+module use "$installpath"/bisheng-compiler-2.1.0
+module load "$installpath"/bisheng-compiler-2.1.0/bisheng_modulefiles
+
+bash $dep_dir/hmpi-1.1.1.sh "$buildpath" "$installpath"
+module use "$installpath"/hmpi-1.1.1
+module load "$installpath"/hmpi-1.1.1/hmpi_modulefiles
+
+bash $dep_dir/miniconda-py38_4.11.0-devel.sh "$buildpath" "$installpath"
+module use "$installpath"/miniconda3
+module load "$installpath"/miniconda3/miniconda_py38_modulefiles
+
+bash $dep_dir/openblas-0.3.18.sh "$buildpath" "$installpath"
+bash $dep_dir/lapack-3.8.0.sh "$buildpath" "$installpath"
+module use "$installpath"/openblas
+module load "$installpath"/openblas/OpenBLAS-0.3.18_modulefiles
+
+bash ambertools-21.sh "$buildpath" "$installpath"
+
+mkdir -p pkg/ambertools-21-hpc && cp -r "$installpath"/* pkg/ambertools-21-hpc/
+cat >"pkg/ambertools-21-hpc/run.sh" <<EOF
+#!/bin/bash
+yum install -y m4 environment-modules systemd-devel cmake csh time patch libatomic perl perl-Data-Dumper \\
+autoconf automake libtool numactl binutils valgrind zlib-devel flex wget tar libatomic zlib-devel gcc-c++ git bison bzip2 bzip2-devel libXt-devel libXext-devel libX11-devel libICE-devel libSM-devel
+source /etc/profile &> /dev/null 
+current_dir=\$(cd "\$(dirname "\${BASH_SOURCE[0]}")" &> /dev/null && pwd)
+source \$current_dir/ambertools21/amber.sh
+for d in \$(ls \$current_dir)
+do
+    [[ ! \$d =~ "amber" && ! -f "\$current_dir/\$d" ]] && cd \$current_dir/\$d && module use \$(pwd) && module load \$(pwd)/*modulefiles
+done
+cd \$current_dir
+[[ ! -d "$installpath/hmpi-1.1.1" ]] && mkdir -p $installpath/hmpi-1.1.1 && cp -r \$current_dir/hmpi-1.1.1/* $installpath/hmpi-1.1.1/
+EOF
+cd pkg/ && tar zcvf ambertools-21-hpc.tar.gz ambertools-21-hpc
+
+rm -rf "$buildpath" "$installpath"
diff --git a/LifeSciences/ambertools-21/cmake.defaults.patch b/LifeSciences/ambertools-21/cmake.defaults.patch
new file mode 100644
index 0000000000000000000000000000000000000000..067035e8b7ca4819c66dea3aa6756c2760f9397a
--- /dev/null
+++ b/LifeSciences/ambertools-21/cmake.defaults.patch
@@ -0,0 +1,64 @@
+diff -Nur modify/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp base/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp
+--- modify/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp	2018-06-18 22:24:05.000000000 +0800
++++ base/amber20_src/AmberTools/src/reduce/libpdb/pdb++.cpp	2022-04-11 20:38:28.235163871 +0800
+@@ -19,7 +19,7 @@
+ 
+ #include "pdb++.h"
+ 
+-extern "C" {
++//extern "C" {
+ #ifdef OLD_STD_HDRS
+ #include <string.h>
+ #else
+@@ -27,7 +27,7 @@
+ using std::memset;
+ using std::memcmp;
+ #endif
+-}
++//}
+ 
+ PDB::PDB()
+ {
+diff -Nur modify/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp base/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp
+--- modify/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp	2018-06-18 22:24:05.000000000 +0800
++++ base/amber20_src/AmberTools/src/reduce/libpdb/pdb_type.cpp	2022-04-11 20:38:47.039378191 +0800
+@@ -20,7 +20,7 @@
+ //
+ 
+ # include	"pdb++.h"
+-extern "C" {
++//extern "C" {
+ #ifdef OLD_STD_HDRS
+ #include <ctype.h>
+ #include <string.h>
+@@ -30,7 +30,7 @@
+ using std::islower;
+ using std::toupper;
+ #endif
+-}
++//}
+ #if defined(__DECCXX_VER) || defined(_MSC_VER)
+ #define NEEDSTRCASECMP
+ #endif
+diff -Nur modify/amber20_src/AmberTools/src/sebomd/se_etimer.F base/amber20_src/AmberTools/src/sebomd/se_etimer.F
+--- modify/amber20_src/AmberTools/src/sebomd/se_etimer.F	2018-08-15 19:33:54.000000000 +0800
++++ base/amber20_src/AmberTools/src/sebomd/se_etimer.F	2022-04-11 20:38:06.450915586 +0800
+@@ -6,7 +6,7 @@
+ #ifdef MPI
+ #include "mpif.h"
+ #endif
+-
++      INTEGER :: mclock
+       double precision t
+
+       double precision tnow, t0
+@@ -24,7 +24,7 @@
+ #     if (__GNUC__ == 4 && __GNUC_MINOR__ <= 1)
+       tnow = second()
+ #     else
+-      tnow = 0.01*mclock()
++      tnow = 0.01*mclock()  !gfortran
+ #     endif
+ #  endif
+ #endif
+
diff --git a/LifeSciences/ambertools-21/dependency/bisheng-compiler-2.1.0.sh b/LifeSciences/ambertools-21/dependency/bisheng-compiler-2.1.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..1691b5f801e07d4c9bc8d97927fccf50a0c085e6
--- /dev/null
+++ b/LifeSciences/ambertools-21/dependency/bisheng-compiler-2.1.0.sh
@@ -0,0 +1,42 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash bisheng-compiler-2.1.0.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] && echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] && echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar environment-modules gcc-c++ gcc-gfortran libatomic --nogpgcheck
+
+wget -t 30 -c -P "$buildpath" https://mirrors.huaweicloud.com/kunpeng/archive/compiler/bisheng_compiler/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+tar xf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz -C "$buildpath" && rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux.tar.gz
+mkdir -p "$installpath"/bisheng-compiler-2.1.0 && cp -r "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux/* "$installpath"/bisheng-compiler-2.1.0/
+
+cat >"$installpath/bisheng-compiler-2.1.0/bisheng_modulefiles" <<EOF
+#%Module1.0
+conflict bisheng
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set BISHENG \$pwd
+setenv BISHENG \$BISHENG
+prepend-path PATH \$BISHENG/bin
+prepend-path LD_LIBRARY_PATH \$BISHENG/lib
+EOF
+
+rm -rf "$buildpath"/bisheng-compiler-2.1.0-aarch64-linux
diff --git a/LifeSciences/ambertools-21/dependency/hmpi-1.1.1.sh b/LifeSciences/ambertools-21/dependency/hmpi-1.1.1.sh
new file mode 100644
index 0000000000000000000000000000000000000000..dee980ab70accce5770ccea46d269a359701ba59
--- /dev/null
+++ b/LifeSciences/ambertools-21/dependency/hmpi-1.1.1.sh
@@ -0,0 +1,70 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "bash hmpi-1.1.1.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+[[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]] && echo "请输入正确的构建路径" && exit 1
+[[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]] && echo "请输入正确的安装路径" && exit 1
+
+buildpath=$1
+installpath=$2
+[[ "$buildpath" =~ .*/$ ]] && buildpath=${buildpath%/*}
+[[ "$installpath" =~ .*/$ ]] && installpath=${installpath%/*}
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e
+yum install -y wget tar perl-Data-Dumper autoconf automake libtool numactl binutils systemd-devel valgrind flex environment-modules git --nogpgcheck
+
+download_pkg() {
+    wget -t 30 -c -P "$buildpath" "$1"
+    tar xf "$buildpath"/v1.1.1-huawei.tar.gz -C "$buildpath"
+    rm -rf "$buildpath"/v1.1.1-huawei.tar.gz
+}
+
+download_pkg https://github.com/kunpengcompute/hmpi/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/hucx/archive/refs/tags/v1.1.1-huawei.tar.gz
+download_pkg https://github.com/kunpengcompute/xucg/archive/refs/tags/v1.1.1-huawei.tar.gz
+cp -r "$buildpath"/xucg-1.1.1-huawei/* "$buildpath"/hucx-1.1.1-huawei/src/ucg/
+cd "$buildpath"/hucx-1.1.1-huawei
+git init && ./autogen.sh
+./contrib/configure-opt --prefix="$installpath"/hmpi-1.1.1/hucx-1.1.1-huawei --disable-numa CC=clang CXX=clang++ FC=flang
+for file in $(find . -name Makefile); do sed -i "s/-Werror//g" "$file"; done
+for file in $(find . -name Makefile); do sed -i "s/-implicit-function-declaration//g" "$file"; done
+make -j$(nproc)
+make -j$(nproc) install
+export PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/bin:$PATH
+export LD_LIBRARY_PATH=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/lib:$LD_LIBRARY_PATH
+export INCLUDE=$installpath/hmpi-1.1.1/hucx-1.1.1-huawei/include:$INCLUDE
+cd "$buildpath"/hmpi-1.1.1-huawei
+./autogen.pl CC=clang CXX=clang++ FC=flang
+./configure --prefix="$installpath"/hmpi-1.1.1/hmpi-1.1.1-huawei --with-platform=contrib/platform/mellanox/optimized --enable-mpil-compatibility \
+    --with-ucx="$installpath"/hmpi-1.1.1/hucx-1.1.1-huawei CC=clang CXX=clang++ FC=flang
+make -j$(nproc)
+make -j$(nproc) install
+cat >"$installpath/hmpi-1.1.1/hmpi_modulefiles" <<EOF
+#%Module1.0
+conflict hmpi
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set HUCX \$pwd/hucx-1.1.1-huawei
+setenv HUCX \$HUCX
+prepend-path PATH \$HUCX/bin
+prepend-path LD_LIBRARY_PATH \$HUCX/lib
+prepend-path INCLUDE \$HUCX/include
+set HMPI \$pwd/hmpi-1.1.1-huawei
+setenv HMPI \$HMPI
+prepend-path PATH \$HMPI/bin
+prepend-path LD_LIBRARY_PATH \$HMPI/lib
+prepend-path INCLUDE \$HMPI/include
+EOF
+
+rm -rf "$buildpath"/xucg-1.1.1-huawei "$buildpath"/hucx-1.1.1-huawei "$buildpath"/hmpi-1.1.1-huawei
diff --git a/LifeSciences/ambertools-21/dependency/lapack-3.8.0.sh b/LifeSciences/ambertools-21/dependency/lapack-3.8.0.sh
new file mode 100644
index 0000000000000000000000000000000000000000..b8717d14f3dc09528125388d10e0ce911b1ded77
--- /dev/null
+++ b/LifeSciences/ambertools-21/dependency/lapack-3.8.0.sh
@@ -0,0 +1,58 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./lapack-0.3.18.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then
+    echo "请输入正确的构建路径"
+    exit 1
+fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then
+    echo "请输入正确的安装路径"
+    exit 1
+fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e 
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 20 -c -P "$buildpath" http://www.netlib.org/lapack/lapack-3.8.0.tar.gz
+tar xf "$buildpath"/lapack-3.8.0.tar.gz -C "$buildpath" && rm -rf "$buildpath"/lapack-3.8.0.tar.gz
+cd "$buildpath"/lapack-3.8.0 || exit 
+sed -i '1i\                 REAL Function etime(time)' INSTALL/second_INT_ETIME.f
+sed -i '2i\                  REAL time(2)' INSTALL/second_INT_ETIME.f
+sed -i '3i\                  Call Cpu_Time(etime)' INSTALL/second_INT_ETIME.f
+sed -i '4i\                  time(1) = etime' INSTALL/second_INT_ETIME.f
+sed -i '5i\                  time(2) = 0' INSTALL/second_INT_ETIME.f
+sed -i '6i\                 End Function' INSTALL/second_INT_ETIME.f
+sed -i 's/REAL               ETIME//g' INSTALL/second_INT_ETIME.f
+sed -i 's/INTRINSIC          ETIME//g' INSTALL/second_INT_ETIME.f
+sed -i 's/T1 = ETIME( TARRAY )/T1 = etime( TARRAY )/g' INSTALL/second_INT_ETIME.f
+
+sed -i '1i\                 REAL Function etime(time)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '2i\                  REAL time(2)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '3i\                  Call Cpu_Time(etime)' INSTALL/dsecnd_INT_ETIME.f
+sed -i '4i\                  time(1) = etime' INSTALL/dsecnd_INT_ETIME.f
+sed -i '5i\                  time(2) = 0' INSTALL/dsecnd_INT_ETIME.f
+sed -i '6i\                 End Function' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/REAL               ETIME//g' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/INTRINSIC          ETIME//g' INSTALL/dsecnd_INT_ETIME.f
+sed -i 's/T1 = ETIME( TARRAY )/T1 = etime( TARRAY )/g' INSTALL/dsecnd_INT_ETIME.f
+
+cp make.inc.example make.inc
+sed -i 's/gcc/clang/g' make.inc
+sed -i 's/gfortran/flang/g' make.inc
+sed -i 's/librefblas.a/libblas.a/g' make.inc
+
+make -j $(nproc)
+cp *.a "$installpath"/openblas/lib
+
+rm -rf "$buildpath"/lapack-3.8.0
diff --git a/LifeSciences/ambertools-21/dependency/miniconda-py38_4.11.0-devel.sh b/LifeSciences/ambertools-21/dependency/miniconda-py38_4.11.0-devel.sh
new file mode 100644
index 0000000000000000000000000000000000000000..fd5ee410a18ac774610d1ca25133f0bd08c37d65
--- /dev/null
+++ b/LifeSciences/ambertools-21/dependency/miniconda-py38_4.11.0-devel.sh
@@ -0,0 +1,50 @@
+#!/bin/bash
+
+### 使用Miniconda3来安装python依赖
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./miniconda-py38_4.11.0-devel.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then
+    echo "请输入正确的构建路径"
+    exit 1
+fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then
+    echo "请输入正确的安装路径"
+    exit 1
+fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e 
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 30 -c -P "$buildpath" https://repo.anaconda.com/miniconda/Miniconda3-py38_4.11.0-Linux-aarch64.sh
+
+sh "$buildpath"/Miniconda3-py38_4.11.0-Linux-aarch64.sh -b -p "$installpath"/miniconda3
+
+"$installpath"/miniconda3/condabin/conda install -y numpy scipy matplotlib setuptools
+"$installpath"/miniconda3/bin/pip3 install mpi4py
+
+cat >"$installpath/miniconda3/miniconda_py38_modulefiles" <<EOF
+#%Module1.0
+conflict miniconda_py38
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set MINICONDA_PY38 \$pwd
+setenv MINICONDA_PY38 \$MINICONDA_PY38
+prepend-path PATH \$MINICONDA_PY38/bin
+EOF
+
+rm -rf "$buildpath"/Miniconda3-py38_4.11.0-Linux-aarch64.sh
diff --git a/LifeSciences/ambertools-21/dependency/openblas-0.3.18.sh b/LifeSciences/ambertools-21/dependency/openblas-0.3.18.sh
new file mode 100644
index 0000000000000000000000000000000000000000..77fcc198422d80994be496ba4b761ba9aaf96756
--- /dev/null
+++ b/LifeSciences/ambertools-21/dependency/openblas-0.3.18.sh
@@ -0,0 +1,49 @@
+#!/bin/bash
+
+if [[ $# -ne 2 ]]; then
+    echo "The format is as follows:"
+    echo "./openblas-0.3.18.sh buildpath installpath"
+    echo ":param buildpath: 应用构建绝对路径"
+    echo ":param installpath: 应用安装绝对路径"
+    exit 1
+fi
+
+if [[ ! "$1" =~ ^/.* || ! -d "$1" || "$1" = "/" ]]; then
+    echo "请输入正确的构建路径"
+    exit 1
+fi
+if [[ ! "$2" =~ ^/.* || ! -d "$2" || "$2" = "/" ]]; then
+    echo "请输入正确的安装路径"
+    exit 1
+fi
+
+buildpath=$1
+installpath=$2
+if [[ "$1" =~ .*/$ ]]; then buildpath=${buildpath%/*}; fi
+if [[ "$2" =~ .*/$ ]]; then installpath=${installpath%/*}; fi
+[[ "$buildpath" == "$installpath" ]] && echo "构建路径与安装路径需为不同路径" && exit 1
+set -e 
+yum install -y wget tar cmake environment-modules --nogpgcheck
+wget -t 30 -c -P "$buildpath" https://github.com/xianyi/OpenBLAS/releases/download/v0.3.18/OpenBLAS-0.3.18.tar.gz
+tar xf "$buildpath"/OpenBLAS-0.3.18.tar.gz -C "$buildpath" && rm -rf "$buildpath"/OpenBLAS-0.3.18.tar.gz
+cd "$buildpath"/OpenBLAS-0.3.18 || exit
+
+CC=clang CXX=clang++ FC=flang \
+    make -j$(nproc) && make -j$(nproc) PREFIX="$installpath"/openblas install
+
+cat >"$installpath/openblas/OpenBLAS-0.3.18_modulefiles" <<EOF
+#%Module1.0
+conflict OpenBLAS
+variable modfile [file normalize [info script]]
+proc getModulefileDir {} {
+    variable modfile
+    set modfile_path [file dirname \$modfile]
+    return \$modfile_path
+}
+set pwd [getModulefileDir]
+set OpenBLAS \$pwd
+setenv OpenBLAS \$OpenBLAS
+prepend-path LD_LIBRARY_PATH \$OpenBLAS/lib
+EOF
+
+rm -rf "$buildpath"/OpenBLAS-0.3.18
diff --git "a/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" "b/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..c3cab0b73162a30a558255f308fb84afdf21ae32
Binary files /dev/null and "b/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\346\265\213\350\257\225\346\212\245\345\221\212.docx" differ
diff --git "a/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" "b/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..b8d6cf03057954fbc34b9c91e047897a9792ca6c
Binary files /dev/null and "b/LifeSciences/ambertools-21/doc/AmberTools-21\345\272\224\347\224\250\347\247\273\346\244\215\346\214\207\345\215\227.docx" differ
diff --git "a/LifeSciences/ambertools-21/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" "b/LifeSciences/ambertools-21/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx"
new file mode 100644
index 0000000000000000000000000000000000000000..f697039ec50f41a8fd2cc473f358616e2baa89bd
Binary files /dev/null and "b/LifeSciences/ambertools-21/doc/\351\262\262\351\271\217\345\237\272\345\272\247\350\275\257\344\273\266\346\220\255\345\273\272\346\214\207\345\215\227.docx" differ
diff --git a/README.md b/README.md
index 5332d395575b39e3e2bbab3918b29effeab87d33..3e73caf4321f8015ca5c65cdf63d55e482361bd3 100644
--- a/README.md
+++ b/README.md
@@ -16,5 +16,4 @@ HPC Software List:
 - repositories: LifeSciences/Muscle-5.1
 - repositories: LifeSciences/3d-dna-180922
 - repositories: LifeSciences/featureCounts-2.0.3
-
-
+- repositories: LifeSciences/ambertools-21