diff --git a/hw/virtio/virtio.c b/hw/virtio/virtio.c
index daa82503329154085e8c352de29d8e001c4a8426..0e5b581534fa3653aa7257798cd6ff05eaf8de3c 100644
--- a/hw/virtio/virtio.c
+++ b/hw/virtio/virtio.c
@@ -1699,6 +1699,7 @@ void virtio_delete_queue(VirtQueue *vq)
     vq->vring.num_default = 0;
     vq->handle_output = NULL;
     vq->handle_aio_output = NULL;
+    virtio_virtqueue_reset_region_cache(vq);
 }
 
 void virtio_del_queue(VirtIODevice *vdev, int n)