diff --git a/python-urllib3.spec b/python-urllib3.spec
index dec7db6e8737adbbefc2e29d437a3700de6fa5b8..b92262b08987ce8acfbf1f1540767b9a932bf374 100644
--- a/python-urllib3.spec
+++ b/python-urllib3.spec
@@ -3,7 +3,7 @@
 
 Name:           python-%{srcname}
 Version:        1.26.3
-Release:        3
+Release:        4
 Summary:        Sanity-friendly HTTP client for Python
 License:        MIT
 URL:            https://urllib3.readthedocs.io
@@ -26,7 +26,7 @@ BuildRequires:  python3-devel
 BuildRequires:  python3-setuptools
 
 %if %{with tests}
-BuildRequires:  python3-nose python3-mock python3-six python-idna python-dateutil
+BuildRequires:  python3-mock python3-six python-idna python-dateutil
 BuildRequires:  python3-pysocks python3-pytest python3-tornado python-trustme
 %endif
 
@@ -74,6 +74,9 @@ PYTHONPATH=%{buildroot}%{python3_sitelib}:%{python3_sitelib} %{__python3} -m pyt
 %{python3_sitelib}/urllib3-*.egg-info
 
 %changelog
+* Wed Mar 02 2022 huangtianhua <huangtianhua@huawei.com> - 1.26.3-4
+- Remove python3-nose BuildRequires
+
 * Mon Jul 5 2021 zhanzhimin <zhanzhimin@huawei.com> - 1.26.3-3
 - fix CVE-2021-33503