diff --git a/scipy-1.6.2.tar.gz b/scipy-1.10.1.tar.gz
similarity index 57%
rename from scipy-1.6.2.tar.gz
rename to scipy-1.10.1.tar.gz
index 0785b679766aa7f0ad73e9b8b2b2843fee1faccd..cdfd6ef9b19213c870dc96a58ff6eb7d60ba4a6a 100644
Binary files a/scipy-1.6.2.tar.gz and b/scipy-1.10.1.tar.gz differ
diff --git a/scipy.spec b/scipy.spec
index f2ef21fae372857093bcbe8f3b4a3f56f897eaa8..b832dda08baed2d0f057e2407ad52caf0a42fc81 100644
--- a/scipy.spec
+++ b/scipy.spec
@@ -1,7 +1,7 @@
 %global py_setup_args config_fc --fcompiler=gnu95 --noarch
 %global debug_package %{nil}
 Name: scipy
-Version: 1.6.2
+Version: 1.10.1
 Release: 1
 Summary: A Python-based ecosystem of open-source software for mathematics, science, and engineering
 License: Qhull and Apache-2.0
@@ -55,6 +55,7 @@ cp -a . %{py3dir}
 
 
 %build
+export SCIPY_USE_PYTHRAN=0
 export CFLAGS="$RPM_OPT_FLAGS -lm"
 export LDFLAGS="$RPM_LD_FLAGS -Wall -shared"
 pushd %{py3dir}
@@ -64,6 +65,7 @@ env FFLAGS="$RPM_OPT_FLAGS -fPIC -w -fallow-argument-mismatch -O2"\
 popd
 
 %install
+export SCIPY_USE_PYTHRAN=0
 export CFLAGS="$RPM_OPT_FLAGS -lm"
 export LDFLAGS="$RPM_LD_FLAGS -Wall -shared"
 
@@ -98,6 +100,9 @@ echo "%{_libdir}/%{name}" >> $RPM_BUILD_ROOT/etc/ld.so.conf.d/%{name}-%{_arch}.c
 %config(noreplace) /etc/ld.so.conf.d/*
 
 %changelog
+* Mon Jul 10 2023 wangkai <13474090681@163.com> - 1.10.1-1
+- Update to 1.10.1
+
 * Mon Dec 13 2021 zhouwenpei <zhouwenpei1@huawei.com> - 1.6.2-1
 - upgrade to 1.6.2